iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation

We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (~24 million autosomal CpG sites), whole-genome (~9 million single-nucleotide variants), and whole-transcriptome (>14 000 genes) data for CD4(+) T-lymphocytes, mono...

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Autores principales: Komaki, Shohei, Shiwa, Yuh, Furukawa, Ryohei, Hachiya, Tsuyoshi, Ohmomo, Hideki, Otomo, Ryo, Satoh, Mamoru, Hitomi, Jiro, Sobue, Kenji, Sasaki, Makoto, Shimizu, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Data Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874393/
https://www.ncbi.nlm.nih.gov/pubmed/29619235
http://dx.doi.org/10.1038/hgv.2018.8
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author Komaki, Shohei
Shiwa, Yuh
Furukawa, Ryohei
Hachiya, Tsuyoshi
Ohmomo, Hideki
Otomo, Ryo
Satoh, Mamoru
Hitomi, Jiro
Sobue, Kenji
Sasaki, Makoto
Shimizu, Atsushi
author_facet Komaki, Shohei
Shiwa, Yuh
Furukawa, Ryohei
Hachiya, Tsuyoshi
Ohmomo, Hideki
Otomo, Ryo
Satoh, Mamoru
Hitomi, Jiro
Sobue, Kenji
Sasaki, Makoto
Shimizu, Atsushi
author_sort Komaki, Shohei
collection PubMed
description We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (~24 million autosomal CpG sites), whole-genome (~9 million single-nucleotide variants), and whole-transcriptome (>14 000 genes) data for CD4(+) T-lymphocytes, monocytes, and neutrophils collected from approximately 100 subjects. These data were obtained from whole-genome bisulfite sequencing, whole-genome sequencing, and whole-transcriptome sequencing, making iMETHYL a comprehensive database.
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spelling pubmed-58743932018-04-04 iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation Komaki, Shohei Shiwa, Yuh Furukawa, Ryohei Hachiya, Tsuyoshi Ohmomo, Hideki Otomo, Ryo Satoh, Mamoru Hitomi, Jiro Sobue, Kenji Sasaki, Makoto Shimizu, Atsushi Hum Genome Var Data Report We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (~24 million autosomal CpG sites), whole-genome (~9 million single-nucleotide variants), and whole-transcriptome (>14 000 genes) data for CD4(+) T-lymphocytes, monocytes, and neutrophils collected from approximately 100 subjects. These data were obtained from whole-genome bisulfite sequencing, whole-genome sequencing, and whole-transcriptome sequencing, making iMETHYL a comprehensive database. Nature Publishing Group 2018-03-29 /pmc/articles/PMC5874393/ /pubmed/29619235 http://dx.doi.org/10.1038/hgv.2018.8 Text en Copyright © 2018 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Data Report
Komaki, Shohei
Shiwa, Yuh
Furukawa, Ryohei
Hachiya, Tsuyoshi
Ohmomo, Hideki
Otomo, Ryo
Satoh, Mamoru
Hitomi, Jiro
Sobue, Kenji
Sasaki, Makoto
Shimizu, Atsushi
iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation
title iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation
title_full iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation
title_fullStr iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation
title_full_unstemmed iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation
title_short iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation
title_sort imethyl: an integrative database of human dna methylation, gene expression, and genomic variation
topic Data Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874393/
https://www.ncbi.nlm.nih.gov/pubmed/29619235
http://dx.doi.org/10.1038/hgv.2018.8
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