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iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation
We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (~24 million autosomal CpG sites), whole-genome (~9 million single-nucleotide variants), and whole-transcriptome (>14 000 genes) data for CD4(+) T-lymphocytes, mono...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874393/ https://www.ncbi.nlm.nih.gov/pubmed/29619235 http://dx.doi.org/10.1038/hgv.2018.8 |
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author | Komaki, Shohei Shiwa, Yuh Furukawa, Ryohei Hachiya, Tsuyoshi Ohmomo, Hideki Otomo, Ryo Satoh, Mamoru Hitomi, Jiro Sobue, Kenji Sasaki, Makoto Shimizu, Atsushi |
author_facet | Komaki, Shohei Shiwa, Yuh Furukawa, Ryohei Hachiya, Tsuyoshi Ohmomo, Hideki Otomo, Ryo Satoh, Mamoru Hitomi, Jiro Sobue, Kenji Sasaki, Makoto Shimizu, Atsushi |
author_sort | Komaki, Shohei |
collection | PubMed |
description | We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (~24 million autosomal CpG sites), whole-genome (~9 million single-nucleotide variants), and whole-transcriptome (>14 000 genes) data for CD4(+) T-lymphocytes, monocytes, and neutrophils collected from approximately 100 subjects. These data were obtained from whole-genome bisulfite sequencing, whole-genome sequencing, and whole-transcriptome sequencing, making iMETHYL a comprehensive database. |
format | Online Article Text |
id | pubmed-5874393 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-58743932018-04-04 iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation Komaki, Shohei Shiwa, Yuh Furukawa, Ryohei Hachiya, Tsuyoshi Ohmomo, Hideki Otomo, Ryo Satoh, Mamoru Hitomi, Jiro Sobue, Kenji Sasaki, Makoto Shimizu, Atsushi Hum Genome Var Data Report We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (~24 million autosomal CpG sites), whole-genome (~9 million single-nucleotide variants), and whole-transcriptome (>14 000 genes) data for CD4(+) T-lymphocytes, monocytes, and neutrophils collected from approximately 100 subjects. These data were obtained from whole-genome bisulfite sequencing, whole-genome sequencing, and whole-transcriptome sequencing, making iMETHYL a comprehensive database. Nature Publishing Group 2018-03-29 /pmc/articles/PMC5874393/ /pubmed/29619235 http://dx.doi.org/10.1038/hgv.2018.8 Text en Copyright © 2018 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Data Report Komaki, Shohei Shiwa, Yuh Furukawa, Ryohei Hachiya, Tsuyoshi Ohmomo, Hideki Otomo, Ryo Satoh, Mamoru Hitomi, Jiro Sobue, Kenji Sasaki, Makoto Shimizu, Atsushi iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation |
title | iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation |
title_full | iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation |
title_fullStr | iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation |
title_full_unstemmed | iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation |
title_short | iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation |
title_sort | imethyl: an integrative database of human dna methylation, gene expression, and genomic variation |
topic | Data Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874393/ https://www.ncbi.nlm.nih.gov/pubmed/29619235 http://dx.doi.org/10.1038/hgv.2018.8 |
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