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The Location of Conjunctivochalasis and Its Clinical Correlation with the Severity of Dry Eye Symptoms

Background: We aimed to investigate the clinical importance of conjunctivochalasis (CCH) and, further, to implement a new CCH classification system. Methods: 60 eyes of patients with whom, upon clinical examination, CCH was diagnosed were investigated for the presence of symptoms and signs character...

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Autores principales: Dalianis, Georgios, Trivli, Alexandra, Terzidou, Chryssa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874577/
https://www.ncbi.nlm.nih.gov/pubmed/29361769
http://dx.doi.org/10.3390/medicines5010012
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author Dalianis, Georgios
Trivli, Alexandra
Terzidou, Chryssa
author_facet Dalianis, Georgios
Trivli, Alexandra
Terzidou, Chryssa
author_sort Dalianis, Georgios
collection PubMed
description Background: We aimed to investigate the clinical importance of conjunctivochalasis (CCH) and, further, to implement a new CCH classification system. Methods: 60 eyes of patients with whom, upon clinical examination, CCH was diagnosed were investigated for the presence of symptoms and signs characteristic of dry eye. The eyes were grouped based on two stages of severity, Stage 1 (minimal/mild) and Stage 2 (medium/severe), for each nasal, middle, and temporal position, and on the extent of CCH folds in each site. Results: In 40 (66.6%) out of 60 eyes, symptoms and signs of CCH were manifest: pain in 25 (41.6%), epiphora in 25 (41.6%), and lacrimal punctum obstruction from conjunctival folds in 22 (36.6%) eyes. Depending on the position of CCH, a greater percentage of symptoms appeared in Stage 2 in the nasal position (78.9%), followed by middle (68.7%) and temporal positions (60%). When TBUT values were compared, statistically significant differences were found proportional to grading (p < 0.001) and position (nasal more severe than temporal, p < 0.001), and such differences were also found when TBUT values of all eyes were compared with those of symptomatic eyes (p = 0.01) and with those of symptom-free eyes (p = 0.002). Conclusions: CCH is a rather frequent and commonly unrecognized condition that should always be considered in differential diagnoses of dry eye.
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spelling pubmed-58745772018-03-30 The Location of Conjunctivochalasis and Its Clinical Correlation with the Severity of Dry Eye Symptoms Dalianis, Georgios Trivli, Alexandra Terzidou, Chryssa Medicines (Basel) Article Background: We aimed to investigate the clinical importance of conjunctivochalasis (CCH) and, further, to implement a new CCH classification system. Methods: 60 eyes of patients with whom, upon clinical examination, CCH was diagnosed were investigated for the presence of symptoms and signs characteristic of dry eye. The eyes were grouped based on two stages of severity, Stage 1 (minimal/mild) and Stage 2 (medium/severe), for each nasal, middle, and temporal position, and on the extent of CCH folds in each site. Results: In 40 (66.6%) out of 60 eyes, symptoms and signs of CCH were manifest: pain in 25 (41.6%), epiphora in 25 (41.6%), and lacrimal punctum obstruction from conjunctival folds in 22 (36.6%) eyes. Depending on the position of CCH, a greater percentage of symptoms appeared in Stage 2 in the nasal position (78.9%), followed by middle (68.7%) and temporal positions (60%). When TBUT values were compared, statistically significant differences were found proportional to grading (p < 0.001) and position (nasal more severe than temporal, p < 0.001), and such differences were also found when TBUT values of all eyes were compared with those of symptomatic eyes (p = 0.01) and with those of symptom-free eyes (p = 0.002). Conclusions: CCH is a rather frequent and commonly unrecognized condition that should always be considered in differential diagnoses of dry eye. MDPI 2018-01-22 /pmc/articles/PMC5874577/ /pubmed/29361769 http://dx.doi.org/10.3390/medicines5010012 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dalianis, Georgios
Trivli, Alexandra
Terzidou, Chryssa
The Location of Conjunctivochalasis and Its Clinical Correlation with the Severity of Dry Eye Symptoms
title The Location of Conjunctivochalasis and Its Clinical Correlation with the Severity of Dry Eye Symptoms
title_full The Location of Conjunctivochalasis and Its Clinical Correlation with the Severity of Dry Eye Symptoms
title_fullStr The Location of Conjunctivochalasis and Its Clinical Correlation with the Severity of Dry Eye Symptoms
title_full_unstemmed The Location of Conjunctivochalasis and Its Clinical Correlation with the Severity of Dry Eye Symptoms
title_short The Location of Conjunctivochalasis and Its Clinical Correlation with the Severity of Dry Eye Symptoms
title_sort location of conjunctivochalasis and its clinical correlation with the severity of dry eye symptoms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874577/
https://www.ncbi.nlm.nih.gov/pubmed/29361769
http://dx.doi.org/10.3390/medicines5010012
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