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Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness
Carbonic anhydrase IX has been under intensive investigation as a therapeutic target in cancer. Studies demonstrate that this enzyme has a key role in pH regulation in cancer cells, allowing these cells to adapt to the adverse conditions of the tumour microenviroment. Novel CAIX inhibitors have show...
Autores principales: | Ward, Carol, Meehan, James, Gray, Mark, Kunkler, Ian H., Langdon, Simon P., Argyle, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874614/ https://www.ncbi.nlm.nih.gov/pubmed/29439394 http://dx.doi.org/10.3390/metabo8010013 |
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