Cargando…
Updates in the Development of ImmunoRNases for the Selective Killing of Tumor Cells
Targeted cancer therapy includes, amongst others, antibody-based delivery of toxic payloads to selectively eliminate tumor cells. This payload can be either a synthetic small molecule drug composing an antibody-drug conjugate (ADC) or a cytotoxic protein composing an immunotoxin (IT). Non-human cyto...
Autores principales: | Jordaan, Sandra, Akinrinmade, Olusiji A., Nachreiner, Thomas, Cremer, Christian, Naran, Krupa, Chetty, Shivan, Barth, Stefan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874685/ https://www.ncbi.nlm.nih.gov/pubmed/29510557 http://dx.doi.org/10.3390/biomedicines6010028 |
Ejemplares similares
-
Human MAP Tau Based Targeted Cytolytic Fusion Proteins
por: Akinrinmade, Olusiji A., et al.
Publicado: (2017) -
Targeted human cytolytic fusion proteins at the cutting edge: harnessing the apoptosis-inducing properties of human enzymes for the selective elimination of tumor cells
por: Mungra, Neelakshi, et al.
Publicado: (2019) -
A novel fully human antitumour immunoRNase targeting ErbB2-positive tumours
por: Borriello, M, et al.
Publicado: (2011) -
A novel fully human anti-NCL immunoRNase for triple-negative breast cancer therapy
por: D'Avino, Chiara, et al.
Publicado: (2016) -
Human Granzyme B Based Targeted Cytolytic Fusion Proteins
por: Hlongwane, Precious, et al.
Publicado: (2018)