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Role of Akt Isoforms Controlling Cancer Stem Cell Survival, Phenotype and Self-Renewal
The cancer stem cell (CSC) hypothesis suggests that tumours are maintained by a subpopulation of cells with stem cell properties. Although the existence of CSCs was initially described in human leukaemia, less evidence exists for CSCs in solid tumours. Recently, a CD133+ cell subpopulation was isola...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874686/ https://www.ncbi.nlm.nih.gov/pubmed/29518912 http://dx.doi.org/10.3390/biomedicines6010029 |