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Alpha-Secretase ADAM10 Regulation: Insights into Alzheimer’s Disease Treatment

ADAM (a disintegrin and metalloproteinase) is a family of widely expressed, transmembrane and secreted proteins of approximately 750 amino acids in length with functions in cell adhesion and proteolytic processing of the ectodomains of diverse cell-surface receptors and signaling molecules. ADAM10 i...

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Detalles Bibliográficos
Autores principales: Peron, Rafaela, Vatanabe, Izabela Pereira, Manzine, Patricia Regina, Camins, Antoni, Cominetti, Márcia Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874708/
https://www.ncbi.nlm.nih.gov/pubmed/29382156
http://dx.doi.org/10.3390/ph11010012