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Dose comparison between Gafchromic film, XiO, and Monaco treatment planning systems in a novel pelvic phantom that contains a titanium hip prosthesis

The presence of metallic prostheses during external beam radiotherapy of malignancies in the pelvic region has the potential to strongly influence the dose distribution to the target and to tissue surrounded by the prostheses. This study systematically investigates the perturbation effects of unilat...

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Autores principales: Ade, Nicholas, du Plessis, F.C.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874810/
https://www.ncbi.nlm.nih.gov/pubmed/28741892
http://dx.doi.org/10.1002/acm2.12141
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author Ade, Nicholas
du Plessis, F.C.P.
author_facet Ade, Nicholas
du Plessis, F.C.P.
author_sort Ade, Nicholas
collection PubMed
description The presence of metallic prostheses during external beam radiotherapy of malignancies in the pelvic region has the potential to strongly influence the dose distribution to the target and to tissue surrounded by the prostheses. This study systematically investigates the perturbation effects of unilateral titanium prosthesis on 6 and 15 MV photon beam dose distributions using Gafchromic EBT2 film measurements in a novel pelvic phantom made out of a stack of nylon slices. Comparisons were also made between the film data and dose calculations made on XiO and Monaco treatment planning systems. The collapsed cone algorithm was chosen for the XiO and the Monte Carlo algorithm used on Monaco is XVMC. Transmission measurements were taken using a narrow‐beam geometry to determine the mass attenuation coefficient of nylon = 0.0458 cm(2)/g and for a water‐equivalent RW3 phantom, it was 0.0465 cm(2)/g. The perturbation effects of the prosthesis on dose distributions were investigated by measuring and comparing dose maps and profiles. The magnitude of dose perturbations was quantified by calculating dose enhancement and reduction factors using field sizes of 3 × 3, 5 × 5, 10 × 10, and 15 × 15 cm(2). For the studied beams and field sizes, dose enhancements between 21 and 30% and dose reductions between 15 and 21% were observed at the nylon‐prosthesis interface on the proximal and distal sides of the prosthesis for film measurements. The dose escalation increases with beam energy, and the dose reduction due to attenuation decreases with increasing beam energy when compared to unattenuated beam data. A comparison of film and XiO depth doses for the studied fields gave relative errors between 1.1 and 23.2% at the proximal and distal interfaces of the Ti prosthesis. Also, relative errors < 4.0% were obtained between film and Monaco dose data outside the prosthesis for 6 and 15 MV lateral opposing fields.
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spelling pubmed-58748102018-04-02 Dose comparison between Gafchromic film, XiO, and Monaco treatment planning systems in a novel pelvic phantom that contains a titanium hip prosthesis Ade, Nicholas du Plessis, F.C.P. J Appl Clin Med Phys Radiation Oncology Physics The presence of metallic prostheses during external beam radiotherapy of malignancies in the pelvic region has the potential to strongly influence the dose distribution to the target and to tissue surrounded by the prostheses. This study systematically investigates the perturbation effects of unilateral titanium prosthesis on 6 and 15 MV photon beam dose distributions using Gafchromic EBT2 film measurements in a novel pelvic phantom made out of a stack of nylon slices. Comparisons were also made between the film data and dose calculations made on XiO and Monaco treatment planning systems. The collapsed cone algorithm was chosen for the XiO and the Monte Carlo algorithm used on Monaco is XVMC. Transmission measurements were taken using a narrow‐beam geometry to determine the mass attenuation coefficient of nylon = 0.0458 cm(2)/g and for a water‐equivalent RW3 phantom, it was 0.0465 cm(2)/g. The perturbation effects of the prosthesis on dose distributions were investigated by measuring and comparing dose maps and profiles. The magnitude of dose perturbations was quantified by calculating dose enhancement and reduction factors using field sizes of 3 × 3, 5 × 5, 10 × 10, and 15 × 15 cm(2). For the studied beams and field sizes, dose enhancements between 21 and 30% and dose reductions between 15 and 21% were observed at the nylon‐prosthesis interface on the proximal and distal sides of the prosthesis for film measurements. The dose escalation increases with beam energy, and the dose reduction due to attenuation decreases with increasing beam energy when compared to unattenuated beam data. A comparison of film and XiO depth doses for the studied fields gave relative errors between 1.1 and 23.2% at the proximal and distal interfaces of the Ti prosthesis. Also, relative errors < 4.0% were obtained between film and Monaco dose data outside the prosthesis for 6 and 15 MV lateral opposing fields. John Wiley and Sons Inc. 2017-07-25 /pmc/articles/PMC5874810/ /pubmed/28741892 http://dx.doi.org/10.1002/acm2.12141 Text en © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Ade, Nicholas
du Plessis, F.C.P.
Dose comparison between Gafchromic film, XiO, and Monaco treatment planning systems in a novel pelvic phantom that contains a titanium hip prosthesis
title Dose comparison between Gafchromic film, XiO, and Monaco treatment planning systems in a novel pelvic phantom that contains a titanium hip prosthesis
title_full Dose comparison between Gafchromic film, XiO, and Monaco treatment planning systems in a novel pelvic phantom that contains a titanium hip prosthesis
title_fullStr Dose comparison between Gafchromic film, XiO, and Monaco treatment planning systems in a novel pelvic phantom that contains a titanium hip prosthesis
title_full_unstemmed Dose comparison between Gafchromic film, XiO, and Monaco treatment planning systems in a novel pelvic phantom that contains a titanium hip prosthesis
title_short Dose comparison between Gafchromic film, XiO, and Monaco treatment planning systems in a novel pelvic phantom that contains a titanium hip prosthesis
title_sort dose comparison between gafchromic film, xio, and monaco treatment planning systems in a novel pelvic phantom that contains a titanium hip prosthesis
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874810/
https://www.ncbi.nlm.nih.gov/pubmed/28741892
http://dx.doi.org/10.1002/acm2.12141
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