Feasibility of Using Gluconolactone, Trehalose and Hydroxy-Propyl Gamma Cyclodextrin to Enhance Bendroflumethiazide Dissolution Using Lyophilisation and Physical Mixing Techniques

Purpose: Hydrophobic drugs are facing a major challenge in dissolution rate enhancement and solubility in aqueous solutions; therefore, a variety of methods have been used to improve dissolution rate and/or solubility of bendroflumethiazide as a model hydrophobic drug. Methods: In this study, two ma...

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Detalles Bibliográficos
Autores principales: Saleh, Ashraf, McGarry, Kenneth, Chaw, Cheng Shu, Elkordy, Amal Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874835/
https://www.ncbi.nlm.nih.gov/pubmed/29389848
http://dx.doi.org/10.3390/pharmaceutics10010022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874835/
https://www.ncbi.nlm.nih.gov/pubmed/29389848
http://dx.doi.org/10.3390/pharmaceutics10010022

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