Cargando…

In Vitro Evaluation of Sunscreen Safety: Effects of the Vehicle and Repeated Applications on Skin Permeation from Topical Formulations

The evaluation of UV-filter in vitro percutaneous absorption allows the estimation of the systemic exposure dose (SED) and the margin of safety (MoS) of sunscreen products. As both the vehicle and pattern of application may affect sunscreen safety and efficacy, we evaluated in vitro release and skin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Montenegro, Lucia, Turnaturi, Rita, Parenti, Carmela, Pasquinucci, Lorella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874840/ https://www.ncbi.nlm.nih.gov/pubmed/29495452 http://dx.doi.org/10.3390/pharmaceutics10010027

Ejemplares similares

Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles
por: Montenegro, Lucia, et al.
Publicado: (2017)

Resveratrol-Loaded Lipid Nanocarriers: Correlation between In Vitro Occlusion Factor and In Vivo Skin Hydrating Effect
por: Montenegro, Lucia, et al.
Publicado: (2017)

Idebenone: Novel Strategies to Improve Its Systemic and Local Efficacy
por: Montenegro, Lucia, et al.
Publicado: (2018)

LP1 and LP2: Dual-Target MOPr/DOPr Ligands as Drug Candidates for Persistent Pain Relief
por: Pasquinucci, Lorella, et al.
Publicado: (2021)

Synthesis and Structure-Activity Relationships of (−)-cis-N-Normetazocine-Based LP1 Derivatives
por: Pasquinucci, Lorella, et al.
Publicado: (2018)

From Plant to Chemistry: Sources of Active Opioid Antinociceptive Principles for Medicinal Chemistry and Drug Design
por: Turnaturi, Rita, et al.
Publicado: (2023)

Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists
por: Turnaturi, Rita, et al.
Publicado: (2018)

Influence of anatomical site and topical formulation on skin penetration of sunscreens
por: Benson, Heather AE, et al.
Publicado: (2005)

The effect of formulation vehicles on the in vitro percutaneous permeation of ibuprofen
por: Stahl, Jessica, et al.
Publicado: (2011)

Evaluation of percutaneous permeation of repellent DEET and sunscreen oxybenzone from emulsion-based formulations in artificial membrane and human skin
por: Wang, Tao, et al.
Publicado: (2014)

Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain
por: Turnaturi, Rita, et al.
Publicado: (2022)

Topical Administration of Cannabidiol: Influence of Vehicle-Related Aspects on Skin Permeation Process
por: Casiraghi, Antonella, et al.
Publicado: (2020)

Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain
por: Vicario, Nunzio, et al.
Publicado: (2022)

The Multimodal MOPr/DOPr Agonist LP2 Reduces Allodynia in Chronic Constriction Injured Rats by Rescue of TGF-β1 Signalling
por: Fidilio, Annamaria, et al.
Publicado: (2021)

Design, Physicochemical Characterization, and In Vitro Permeation of Innovative Resatorvid Topical Formulations for Targeted Skin Drug Delivery
por: Ruiz, Victor H., et al.
Publicado: (2022)

New Insights into the Opioid Analgesic Profile of cis-(−)-N-Normetazocine-derived Ligands
por: Costanzo, Giuliana, et al.
Publicado: (2023)

Ensuring the Safety of Sunscreens, and Their Efficacy in Preventing Skin Cancers: Challenges and Controversies for Clinicians, Formulators, and Regulators
por: Paul, Sharad P.
Publicado: (2019)

Role of sunscreen formulation and photostability to protect the biomechanical barrier function of skin
por: Berkey, Christopher, et al.
Publicado: (2019)

Repeated activation of delta opioid receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opioid receptors-mediated antiallodinic effect
por: Vicario, Nunzio, et al.
Publicado: (2016)

Ondansetron HCl Microemulsions for Transdermal Delivery: Formulation and In Vitro Skin Permeation
por: Malakar, Jadupati, et al.
Publicado: (2012)

The Influence of Formulation and Excipients on Propranolol Skin Permeation and Retention
por: Padula, Cristina, et al.
Publicado: (2018)

The Effect of Sunscreens on the Skin Barrier
por: Gonzalez-Bravo, Alicia, et al.
Publicado: (2022)

Evaluation of Formulation Parameters on Permeation of Ibuprofen from Topical Formulations Using Strat-M(®) Membrane
por: Bolla, Pradeep Kumar, et al.
Publicado: (2020)

The Impact of Flavonoid-Loaded Nanoparticles in the UV Protection and Safety Profile of Topical Sunscreens
por: Fonseca, Magda, et al.
Publicado: (2023)

Nanomicelle formulation for topical delivery of cyclosporine A into the cornea: in vitro mechanism and in vivo permeation evaluation
por: Guo, Chuanlong, et al.
Publicado: (2015)

Quantification of Sunscreen Ethylhexyl Triazone in Topical Skin-Care Products by Normal-Phase TLC/Densitometry
por: Sobanska, Anna W., et al.
Publicado: (2012)

Hydrogel Formulations for Topical Insulin Application: Preparation, Characterization and In Vitro Permeation across the Strat-M(®) Membrane
por: Ostróżka-Cieślik, Aneta, et al.
Publicado: (2023)

In Vitro Ciliotoxicity and Cytotoxicity Testing of Repeated Chronic Exposure to Topical Nasal Formulations for Safety Studies
por: Tratnjek, Larisa, et al.
Publicado: (2021)

Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid
por: Frosini, Sian-Marie, et al.
Publicado: (2017)

Evaluation of Paeonol Skin-Target Delivery from Its Microsponge Formulation: In Vitro Skin Permeation and In Vivo Microdialysis
por: Li, Sha-Sha, et al.
Publicado: (2013)

In Vitro Skin Permeation of Idebenone from Lipid Nanoparticles Containing Chemical Penetration Enhancers
por: Montenegro, Lucia, et al.
Publicado: (2021)

Sunscreen products: Rationale for use, formulation development and regulatory considerations
por: Geoffrey, Kiriiri, et al.
Publicado: (2019)

A Study on Improvement of Solubility of Rofecoxib and its effect on Permeation of Drug from Topical Formulations
por: Kulkarni, Madhur, et al.
Publicado: (2008)

Evaluation of Skin Permeation and Retention of Topical Dapsone in Murine Cutaneous Leishmaniasis Lesions
por: Moreno, Esther, et al.
Publicado: (2019)

Comparison of the In Vitro and Ex Vivo Permeation of Existing Topical Formulations Used in the Treatment of Facial Angiofibroma and Characterization of the Variations Observed
por: Le Guyader, Guillaume, et al.
Publicado: (2020)

Innovative Rocuronium Bromide Topical Formulation for Targeted Skin Drug Delivery: Design, Comprehensive Characterization, In Vitro 2D/3D Human Cell Culture and Permeation
por: Ruiz, Victor H., et al.
Publicado: (2023)

Inhibition of Skin Inflammation by Scytonemin, an Ultraviolet Sunscreen Pigment
por: Kang, Moo Rim, et al.
Publicado: (2020)

Importance of the formulation in the skin delivery of topical diclofenac: not all topical diclofenac formulations are the same
por: Pradal, Julie, et al.
Publicado: (2019)

In Vitro Permeation of Micronized and Nanonized Alaptide from Semisolid Formulations
por: Opatrilova, Radka, et al.
Publicado: (2013)

Contribution of the Hair Follicular Pathway to Total Skin Permeation of Topically Applied and Exposed Chemicals
por: Mohd, Fadli, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_njihtd518o5a5g0ejnjkhj06r2