Microscale 3D Liver Bioreactor for In Vitro Hepatotoxicity Testing under Perfusion Conditions

The accurate prediction of hepatotoxicity demands validated human in vitro models that can close the gap between preclinical animal studies and clinical trials. In this study we investigated the response of primary human liver cells to toxic drug exposure in a perfused microscale 3D liver bioreactor...

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Detalles Bibliográficos
Autores principales: Freyer, Nora, Greuel, Selina, Knöspel, Fanny, Gerstmann, Florian, Storch, Lisa, Damm, Georg, Seehofer, Daniel, Foster Harris, Jennifer, Iyer, Rashi, Schubert, Frank, Zeilinger, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874890/
https://www.ncbi.nlm.nih.gov/pubmed/29543727
http://dx.doi.org/10.3390/bioengineering5010024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874890/
https://www.ncbi.nlm.nih.gov/pubmed/29543727
http://dx.doi.org/10.3390/bioengineering5010024

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