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Microscale 3D Liver Bioreactor for In Vitro Hepatotoxicity Testing under Perfusion Conditions
The accurate prediction of hepatotoxicity demands validated human in vitro models that can close the gap between preclinical animal studies and clinical trials. In this study we investigated the response of primary human liver cells to toxic drug exposure in a perfused microscale 3D liver bioreactor...
Autores principales: | Freyer, Nora, Greuel, Selina, Knöspel, Fanny, Gerstmann, Florian, Storch, Lisa, Damm, Georg, Seehofer, Daniel, Foster Harris, Jennifer, Iyer, Rashi, Schubert, Frank, Zeilinger, Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874890/ https://www.ncbi.nlm.nih.gov/pubmed/29543727 http://dx.doi.org/10.3390/bioengineering5010024 |
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