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Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses

The conformation of the HIV-1 envelope glycoprotein (Env) substantially impacts antibody recognition and antibody-dependent cellular cytotoxicity (ADCC) responses. In the absence of the CD4 receptor at the cell surface, primary Envs sample a “closed” conformation that occludes CD4-induced (CD4i) epi...

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Detalles Bibliográficos
Autores principales:	Richard, Jonathan, Prévost, Jérémie, Baxter, Amy E., von Bredow, Benjamin, Ding, Shilei, Medjahed, Halima, Delgado, Gloria G., Brassard, Nathalie, Stürzel, Christina M., Kirchhoff, Frank, Hahn, Beatrice H., Parsons, Matthew S., Kaufmann, Daniel E., Evans, David T., Finzi, Andrés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874913/ https://www.ncbi.nlm.nih.gov/pubmed/29559570 http://dx.doi.org/10.1128/mBio.00358-18

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