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The role of CT myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma

INTRODUCTION: The spinal cord is poorly visualized on CT images but is well visualized in MRI images. However, implants used for spinal stabilization can produce artifacts on the MRI images which can interfere with identification of the cord. CT myelography in conjunction with CT simulation helps to...

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Autores principales: Sudha, SP, Gopalakrishnan, MS, Saravanan, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874956/
https://www.ncbi.nlm.nih.gov/pubmed/28834112
http://dx.doi.org/10.1002/acm2.12144
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author Sudha, SP
Gopalakrishnan, MS
Saravanan, K
author_facet Sudha, SP
Gopalakrishnan, MS
Saravanan, K
author_sort Sudha, SP
collection PubMed
description INTRODUCTION: The spinal cord is poorly visualized on CT images but is well visualized in MRI images. However, implants used for spinal stabilization can produce artifacts on the MRI images which can interfere with identification of the cord. CT myelography in conjunction with CT simulation helps to clearly delineate the cord. MATERIALS AND METHODS: CT simulation was done in a patient with vertebral hemangioma. Pre‐ and post myelography images were obtained. Two plans were generated on pre and post myelography CT images using Eclipse™ treatment planning system (TPS) version 10.0, Varian Medical Systems, USA. The prescribed total dose to PTV was 40 Gy in 20 fractions. RESULTS: The cord was poorly visualized in the premyelogram CT images. The titanium implants used for spinal cord stabilization produced artifacts in the MRI images. Figure 1 Post myelogram, the contrast lit up the spinal cord. There was an overlap of 0.75 cc volume of the spinal cord with the PTV in the premyelogram images. This volume was reduced to 0 cc in the post myelogram images. There was an overlap of 5.4 cc volume of the PRV of spinal cord with the PTV in the premyelogram images which was reduced to 1 cc in the post myelogram images. The overlap region between the PTV and spinal cord received around 71% of the prescribed dose in premyelogram CT could be reduced to 0% in the post myelogram CT. The mean dose received by the overlap PRV spinal cord and PTV could be increased from 70% in the premyelogram to 92% in the post myelogram plans. CONCLUSION: CT myelogram in conjunction with CT simulation is particularly useful in cases where the tumor margin is very close to the cord and spinal implants are causing distortion of magnetic resonance images.
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spelling pubmed-58749562018-04-02 The role of CT myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma Sudha, SP Gopalakrishnan, MS Saravanan, K J Appl Clin Med Phys Radiation Oncology Physics INTRODUCTION: The spinal cord is poorly visualized on CT images but is well visualized in MRI images. However, implants used for spinal stabilization can produce artifacts on the MRI images which can interfere with identification of the cord. CT myelography in conjunction with CT simulation helps to clearly delineate the cord. MATERIALS AND METHODS: CT simulation was done in a patient with vertebral hemangioma. Pre‐ and post myelography images were obtained. Two plans were generated on pre and post myelography CT images using Eclipse™ treatment planning system (TPS) version 10.0, Varian Medical Systems, USA. The prescribed total dose to PTV was 40 Gy in 20 fractions. RESULTS: The cord was poorly visualized in the premyelogram CT images. The titanium implants used for spinal cord stabilization produced artifacts in the MRI images. Figure 1 Post myelogram, the contrast lit up the spinal cord. There was an overlap of 0.75 cc volume of the spinal cord with the PTV in the premyelogram images. This volume was reduced to 0 cc in the post myelogram images. There was an overlap of 5.4 cc volume of the PRV of spinal cord with the PTV in the premyelogram images which was reduced to 1 cc in the post myelogram images. The overlap region between the PTV and spinal cord received around 71% of the prescribed dose in premyelogram CT could be reduced to 0% in the post myelogram CT. The mean dose received by the overlap PRV spinal cord and PTV could be increased from 70% in the premyelogram to 92% in the post myelogram plans. CONCLUSION: CT myelogram in conjunction with CT simulation is particularly useful in cases where the tumor margin is very close to the cord and spinal implants are causing distortion of magnetic resonance images. John Wiley and Sons Inc. 2017-08-18 /pmc/articles/PMC5874956/ /pubmed/28834112 http://dx.doi.org/10.1002/acm2.12144 Text en © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Sudha, SP
Gopalakrishnan, MS
Saravanan, K
The role of CT myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma
title The role of CT myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma
title_full The role of CT myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma
title_fullStr The role of CT myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma
title_full_unstemmed The role of CT myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma
title_short The role of CT myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma
title_sort role of ct myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874956/
https://www.ncbi.nlm.nih.gov/pubmed/28834112
http://dx.doi.org/10.1002/acm2.12144
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