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Commissioning and initial experience with the first clinical gantry‐mounted proton therapy system
The purpose of this study is to describe the comprehensive commissioning process and initial clinical experience of the Mevion S250 proton therapy system, a gantry‐mounted, single‐room proton therapy platform clinically implemented in the S. Lee Kling Proton Therapy Center at Barnes‐Jewish Hospital...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874960/ https://www.ncbi.nlm.nih.gov/pubmed/27074470 http://dx.doi.org/10.1120/jacmp.v17i2.5868 |
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author | Zhao, Tianyu Sun, Baozhou Grantham, Kevin Rankine, Leith Cai, Bin Goddu, Sreekrishna M. Santanam, Lakshmi Knutson, Nels Zhang, Tiezhi Reilly, Michael Bottani, Beth Bradley, Jeffrey Mutic, Sasa Klein, Eric E. |
author_facet | Zhao, Tianyu Sun, Baozhou Grantham, Kevin Rankine, Leith Cai, Bin Goddu, Sreekrishna M. Santanam, Lakshmi Knutson, Nels Zhang, Tiezhi Reilly, Michael Bottani, Beth Bradley, Jeffrey Mutic, Sasa Klein, Eric E. |
author_sort | Zhao, Tianyu |
collection | PubMed |
description | The purpose of this study is to describe the comprehensive commissioning process and initial clinical experience of the Mevion S250 proton therapy system, a gantry‐mounted, single‐room proton therapy platform clinically implemented in the S. Lee Kling Proton Therapy Center at Barnes‐Jewish Hospital in St. Louis, MO, USA. The Mevion S250 system integrates a compact synchrocyclotron with a C‐inner gantry, an image guidance system and a 6D robotic couch into a beam delivery platform. We present our commissioning process and initial clinical experience, including i) CT calibration; ii) beam data acquisition and machine characteristics; iii) dosimetric commissioning of the treatment planning system; iv) validation through the Imaging and Radiation Oncology Core credentialing process, including irradiations on the spine, prostate, brain, and lung phantoms; v) evaluation of localization accuracy of the image guidance system; and vi) initial clinical experience. Clinically, the system operates well and has provided an excellent platform for the treatment of diseases with protons. PACS number(s): 87.55.ne, 87.56.bd |
format | Online Article Text |
id | pubmed-5874960 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-58749602018-04-02 Commissioning and initial experience with the first clinical gantry‐mounted proton therapy system Zhao, Tianyu Sun, Baozhou Grantham, Kevin Rankine, Leith Cai, Bin Goddu, Sreekrishna M. Santanam, Lakshmi Knutson, Nels Zhang, Tiezhi Reilly, Michael Bottani, Beth Bradley, Jeffrey Mutic, Sasa Klein, Eric E. J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study is to describe the comprehensive commissioning process and initial clinical experience of the Mevion S250 proton therapy system, a gantry‐mounted, single‐room proton therapy platform clinically implemented in the S. Lee Kling Proton Therapy Center at Barnes‐Jewish Hospital in St. Louis, MO, USA. The Mevion S250 system integrates a compact synchrocyclotron with a C‐inner gantry, an image guidance system and a 6D robotic couch into a beam delivery platform. We present our commissioning process and initial clinical experience, including i) CT calibration; ii) beam data acquisition and machine characteristics; iii) dosimetric commissioning of the treatment planning system; iv) validation through the Imaging and Radiation Oncology Core credentialing process, including irradiations on the spine, prostate, brain, and lung phantoms; v) evaluation of localization accuracy of the image guidance system; and vi) initial clinical experience. Clinically, the system operates well and has provided an excellent platform for the treatment of diseases with protons. PACS number(s): 87.55.ne, 87.56.bd John Wiley and Sons Inc. 2016-03-08 /pmc/articles/PMC5874960/ /pubmed/27074470 http://dx.doi.org/10.1120/jacmp.v17i2.5868 Text en © 2016 The Authors. This is an open access article under the terms of the http://creativecommons.org/licenses/by/3.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Zhao, Tianyu Sun, Baozhou Grantham, Kevin Rankine, Leith Cai, Bin Goddu, Sreekrishna M. Santanam, Lakshmi Knutson, Nels Zhang, Tiezhi Reilly, Michael Bottani, Beth Bradley, Jeffrey Mutic, Sasa Klein, Eric E. Commissioning and initial experience with the first clinical gantry‐mounted proton therapy system |
title | Commissioning and initial experience with the first clinical gantry‐mounted proton therapy system |
title_full | Commissioning and initial experience with the first clinical gantry‐mounted proton therapy system |
title_fullStr | Commissioning and initial experience with the first clinical gantry‐mounted proton therapy system |
title_full_unstemmed | Commissioning and initial experience with the first clinical gantry‐mounted proton therapy system |
title_short | Commissioning and initial experience with the first clinical gantry‐mounted proton therapy system |
title_sort | commissioning and initial experience with the first clinical gantry‐mounted proton therapy system |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874960/ https://www.ncbi.nlm.nih.gov/pubmed/27074470 http://dx.doi.org/10.1120/jacmp.v17i2.5868 |
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