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QAPA: a new method for the systematic analysis of alternative polyadenylation from RNA-seq data

Alternative polyadenylation (APA) affects most mammalian genes. The genome-wide investigation of APA has been hampered by an inability to reliably profile it using conventional RNA-seq. We describe ‘Quantification of APA’ (QAPA), a method that infers APA from conventional RNA-seq data. QAPA is faste...

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Detalles Bibliográficos
Autores principales:	Ha, Kevin C. H., Blencowe, Benjamin J., Morris, Quaid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874996/ https://www.ncbi.nlm.nih.gov/pubmed/29592814 http://dx.doi.org/10.1186/s13059-018-1414-4

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