Cargando…

Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren's Syndrome

No effective treatment for Sjögren's syndrome (SS), a chronic autoimmune disease affecting mainly salivary and lacrimal glands, is available now. Systemic infusion of allogeneic mesenchymal stem cells (MSCs) isolated from tissues such as bone marrow (BM) alleviated SS in mouse models and a smal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hai, Bo, Shigemoto-Kuroda, Taeko, Zhao, Qingguo, Lee, Ryang Hwa, Liu, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875028/ https://www.ncbi.nlm.nih.gov/pubmed/29736173 http://dx.doi.org/10.1155/2018/2092315

Ejemplares similares

Identification of Molecules Responsible for Therapeutic Effects of Extracellular Vesicles Produced from iPSC-Derived MSCs on Sjo¨gren’s Syndrome
por: Kim, Hyemee, et al.
Publicado: (2021)

Inhibitory Effects of Extracellular Vesicles from iPS-Cell-Derived Mesenchymal Stem Cells on the Onset of Sialadenitis in Sjögren’s Syndrome Are Mediated by Immunomodulatory Splenocytes and Improved by Inhibiting miR-125b
por: Zhao, Qingguo, et al.
Publicado: (2023)

iPSC-MSCs and islet allograft tolerance
por: Wang, Tong-Song, et al.
Publicado: (2015)

Large extracellular vesicles secreted by human iPSC-derived MSCs ameliorate tendinopathy via regulating macrophage heterogeneity
por: Ye, Teng, et al.
Publicado: (2022)

iPSC-Derived MSCs Are a Distinct Entity of MSCs with Higher Therapeutic Potential than Their Donor-Matched Parental MSCs
por: Lee, Hae-Ri, et al.
Publicado: (2023)

Extracellular vesicles from iPSC-MSCs alleviate chemotherapy-induced mouse ovarian damage via the ILK-PI3K/AKT pathway
por: Cao, Rui-Can, et al.
Publicado: (2023)

Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature
por: Spitzhorn, Lucas-Sebastian, et al.
Publicado: (2019)

Low-Intensity Pulsed Ultrasound Promotes Osteogenic Potential of iPSC-Derived MSCs but Fails to Simplify the iPSC-EB-MSC Differentiation Process
por: Hua, Ziyi, et al.
Publicado: (2022)

Connexin 43-Mediated Mitochondrial Transfer of iPSC-MSCs Alleviates Asthma Inflammation
por: Yao, Yin, et al.
Publicado: (2018)

Human iPSC-derived iMSCs improve bone regeneration in mini-pigs
por: Jungbluth, Pascal, et al.
Publicado: (2019)

Extracellular vesicles improve GABAergic transmission in Huntington's disease iPSC-derived neurons
por: Beatriz, Margarida, et al.
Publicado: (2023)

Comparison of human isogeneic Wharton’s jelly MSCs and iPSC-derived MSCs reveals differentiation-dependent metabolic responses to IFNG stimulation
por: Devito, Liani, et al.
Publicado: (2019)

Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p
por: Peng, Wei, et al.
Publicado: (2023)

TWIST1 and TSG6 are coordinately regulated and function as potency biomarkers in human MSCs
por: Lee, Ryang Hwa, et al.
Publicado: (2023)

Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles
por: Otake, Kentaro, et al.
Publicado: (2021)

Immunomodulatory Effect of MSCs and MSCs-Derived Extracellular Vesicles in Systemic Lupus Erythematosus
por: Yang, Chunjuan, et al.
Publicado: (2021)

Therapeutic Potential of a Combination of Electroacupuncture and Human iPSC-Derived Small Extracellular Vesicles for Ischemic Stroke
por: Deng, Peiying, et al.
Publicado: (2022)

MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis
por: Shigemoto-Kuroda, Taeko, et al.
Publicado: (2017)

Sialadenitis
por: De la Rosa Domínguez, Martha María
Publicado: (1987)

Therapeutic Effect of TSG-6 Engineered iPSC-Derived MSCs on Experimental Periodontitis in Rats: A Pilot Study
por: Yang, Heng, et al.
Publicado: (2014)

Human iPSC-MSCs prevent steroid-resistant neutrophilic airway inflammation via modulating Th17 phenotypes
por: Fang, Shu-Bin, et al.
Publicado: (2018)

iPSC-Derived MSCs Versus Originating Jaw Periosteal Cells: Comparison of Resulting Phenotype and Stem Cell Potential
por: Umrath, Felix, et al.
Publicado: (2020)

Human pancreatic islet-derived extracellular vesicles modulate insulin expression in 3D-differentiating iPSC clusters
por: Ribeiro, Diana, et al.
Publicado: (2017)

Lymphocytic sialadenitis of Sjögren's syndrome associated with chronic hepatitis C virus liver disease
por: Haddad, J., et al.
Publicado: (1992)

Extracellular vesicles released from hiPSC-derived MSCs attenuate chronic prostatitis/chronic pelvic pain syndrome in rats by immunoregulation
por: Peng, Xufeng, et al.
Publicado: (2021)

Immunomodulation of MSCs and MSC-Derived Extracellular Vesicles in Osteoarthritis
por: Zhao, Xige, et al.
Publicado: (2020)

iPSC-derived mesenchymal stromal cells are less supportive than primary MSCs for co-culture of hematopoietic progenitor cells
por: Vasko, Theresa, et al.
Publicado: (2016)

Endowing iPSC-Derived MSCs with Angiogenic and Keratinogenic Differentiation Potential: A Promising Cell Source for Skin Tissue Engineering
por: Lin, Weimin, et al.
Publicado: (2018)

Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease
por: Ozay, E. Ilker, et al.
Publicado: (2019)

Electroacupuncture and human iPSC-derived small extracellular vesicles regulate the gut microbiota in ischemic stroke via the brain-gut axis
por: Zhang, Qiongqiong, et al.
Publicado: (2023)

Banking on iPSC- Is it Doable and is it Worthwhile
por: Solomon, Susan, et al.
Publicado: (2014)

Roadblocks in the Path of iPSC to the Clinic
por: Garreta, Elena, et al.
Publicado: (2018)

iPSC Bioprinting: Where are We at?
por: Romanazzo, Sara, et al.
Publicado: (2019)

Maturing iPSC-Derived Cardiomyocytes
por: Tang, Bor Luen
Publicado: (2020)

iPSC for modeling neurodegenerative disorders
por: Valadez-Barba, Valeria, et al.
Publicado: (2020)

Characterizing the secretome of licensed hiPSC-derived MSCs
por: Ramos, Yolande F. M., et al.
Publicado: (2022)

Limitations of the human iPSC-derived neuron model for early-onset Alzheimer’s disease
por: Valdes, Phoebe, et al.
Publicado: (2023)

MSCs vs. iPSCs: Potential in therapeutic applications
por: Thanaskody, Kalaiselvaan, et al.
Publicado: (2022)

Sclerosing Sialadenitis Is Associated With Salivary Gland Hypofunction and a Unique Gene Expression Profile in Sjögren’s Syndrome
por: Yin, Hongen, et al.
Publicado: (2021)

Characteristics of Patients with Primary Sjögren’s Syndrome and Non-specific Chronic Sialadenitis: A Subtype in Elderly Patients
por: Li, Hong-Xia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_diti3qfj9tcvnfsqbi41es9uec