Metabolic investigation in patients with nephrolithiasis

OBJECTIVE: To evaluate the prevalence of metabolic disorders associated with nephrolithiasis in a female population. METHODS: A retrospective study on 1,737 patients with evidence of recent formation of renal stones, being 54% females. The laboratory investigation consisted of at least two samples o...

Descripción completa

Detalles Bibliográficos
Autores principales: dos Santos, Francilayne Moretto, Peres, Aline Krampe, Mandotti, Michel Roberto, Peres, Luis Alberto Batista
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875159/
https://www.ncbi.nlm.nih.gov/pubmed/29267427
http://dx.doi.org/10.1590/S1679-45082017AO4029
Descripción
Sumario:OBJECTIVE: To evaluate the prevalence of metabolic disorders associated with nephrolithiasis in a female population. METHODS: A retrospective study on 1,737 patients with evidence of recent formation of renal stones, being 54% females. The laboratory investigation consisted of at least two samples of blood and 24-hour urine to assess calcium, uric acid, citrate and creatinine levels, qualitative cystinuria, urinary pH following fasting and 12-hour water restriction, urine culture, serum creatinine and parathyroid hormone. RESULTS: The most frequent alterations were hypercalciuria (40.9%), urinary tract infection (23.2%), hypocitraturia (22.4%), low urinary volume (20.5%) and hyperuricosuria (16%). CONCLUSION: The most frequent metabolic alterations in females were hypocitraturia, urinary tract infection, low urinary volume and hyperuricosuria.

Ejemplares similares