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Enhanced Replication of Highly Pathogenic Influenza A(H7N9) Virus in Humans

To clarify the threat posed by emergence of highly pathogenic influenza A(H7N9) virus infection among humans, we characterized the viral polymerase complex. Polymerase basic 2–482R, polymerase basic 2–588V, and polymerase acidic–497R individually or additively enhanced virus polymerase activity, ind...

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Detalles Bibliográficos
Autores principales: Yamayoshi, Seiya, Kiso, Maki, Yasuhara, Atsuhiro, Ito, Mutsumi, Shu, Yuelong, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875272/
https://www.ncbi.nlm.nih.gov/pubmed/29553313
http://dx.doi.org/10.3201/eid2404.171509

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