Direct Whole-Genome Sequencing of Cutaneous Strains of Haemophilus ducreyi

Haemophilus ducreyi, which causes chancroid, has emerged as a cause of pediatric skin disease. Isolation of H. ducreyi in low-income settings is challenging, limiting phylogenetic investigation. Next-generation sequencing demonstrates that cutaneous strains arise from class I and II H. ducreyi clade...

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Detalles Bibliográficos
Autores principales: Marks, Michael, Fookes, Maria, Wagner, Josef, Ghinai, Rosanna, Sokana, Oliver, Sarkodie, Yaw-Adu, Solomon, Anthony W., Mabey, David C.W., Thomson, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875288/
https://www.ncbi.nlm.nih.gov/pubmed/29553314
http://dx.doi.org/10.3201/eid2404.171726
Descripción
Sumario:Haemophilus ducreyi, which causes chancroid, has emerged as a cause of pediatric skin disease. Isolation of H. ducreyi in low-income settings is challenging, limiting phylogenetic investigation. Next-generation sequencing demonstrates that cutaneous strains arise from class I and II H. ducreyi clades and that class II may represent a distinct subspecies.

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