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Direct aperture optimization using an inverse form of back‐projection

Direct aperture optimization (DAO) has been used to produce high dosimetric quality intensity‐modulated radiotherapy (IMRT) treatment plans with fast treatment delivery by directly modeling the multileaf collimator segment shapes and weights. To improve plan quality and reduce treatment time for our...

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Autores principales: Zhu, Xiaofeng, Cullip, Timothy, Tracton, Gregg, Tang, Xiaoli, Lian, Jun, Dooley, John, Chang, Sha X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875482/
https://www.ncbi.nlm.nih.gov/pubmed/24710439
http://dx.doi.org/10.1120/jacmp.v15i2.4545
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author Zhu, Xiaofeng
Cullip, Timothy
Tracton, Gregg
Tang, Xiaoli
Lian, Jun
Dooley, John
Chang, Sha X
author_facet Zhu, Xiaofeng
Cullip, Timothy
Tracton, Gregg
Tang, Xiaoli
Lian, Jun
Dooley, John
Chang, Sha X
author_sort Zhu, Xiaofeng
collection PubMed
description Direct aperture optimization (DAO) has been used to produce high dosimetric quality intensity‐modulated radiotherapy (IMRT) treatment plans with fast treatment delivery by directly modeling the multileaf collimator segment shapes and weights. To improve plan quality and reduce treatment time for our in‐house treatment planning system, we implemented a new DAO approach without using a global objective function (GFO). An index concept is introduced as an inverse form of back‐projection used in the CT multiplicative algebraic reconstruction technique (MART). The index, introduced for IMRT optimization in this work, is analogous to the multiplicand in MART. The index is defined as the ratio of the optima over the current. It is assigned to each voxel and beamlet to optimize the fluence map. The indices for beamlets and segments are used to optimize multileaf collimator (MLC) segment shapes and segment weights, respectively. Preliminary data show that without sacrificing dosimetric quality, the implementation of the DAO reduced average IMRT treatment time from 13 min to 8 min for the prostate, and from 15 min to 9 min for the head and neck using our in‐house treatment planning system PlanUNC. The DAO approach has also shown promise in optimizing rotational IMRT with burst mode in a head and neck test case. PACS number: 87.55.D‐
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spelling pubmed-58754822018-04-02 Direct aperture optimization using an inverse form of back‐projection Zhu, Xiaofeng Cullip, Timothy Tracton, Gregg Tang, Xiaoli Lian, Jun Dooley, John Chang, Sha X J Appl Clin Med Phys Radiation Oncology Physics Direct aperture optimization (DAO) has been used to produce high dosimetric quality intensity‐modulated radiotherapy (IMRT) treatment plans with fast treatment delivery by directly modeling the multileaf collimator segment shapes and weights. To improve plan quality and reduce treatment time for our in‐house treatment planning system, we implemented a new DAO approach without using a global objective function (GFO). An index concept is introduced as an inverse form of back‐projection used in the CT multiplicative algebraic reconstruction technique (MART). The index, introduced for IMRT optimization in this work, is analogous to the multiplicand in MART. The index is defined as the ratio of the optima over the current. It is assigned to each voxel and beamlet to optimize the fluence map. The indices for beamlets and segments are used to optimize multileaf collimator (MLC) segment shapes and segment weights, respectively. Preliminary data show that without sacrificing dosimetric quality, the implementation of the DAO reduced average IMRT treatment time from 13 min to 8 min for the prostate, and from 15 min to 9 min for the head and neck using our in‐house treatment planning system PlanUNC. The DAO approach has also shown promise in optimizing rotational IMRT with burst mode in a head and neck test case. PACS number: 87.55.D‐ John Wiley and Sons Inc. 2014-03-06 /pmc/articles/PMC5875482/ /pubmed/24710439 http://dx.doi.org/10.1120/jacmp.v15i2.4545 Text en © 2014 The Authors. This is an open access article under the terms of the http://creativecommons.org/licenses/by/3.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Zhu, Xiaofeng
Cullip, Timothy
Tracton, Gregg
Tang, Xiaoli
Lian, Jun
Dooley, John
Chang, Sha X
Direct aperture optimization using an inverse form of back‐projection
title Direct aperture optimization using an inverse form of back‐projection
title_full Direct aperture optimization using an inverse form of back‐projection
title_fullStr Direct aperture optimization using an inverse form of back‐projection
title_full_unstemmed Direct aperture optimization using an inverse form of back‐projection
title_short Direct aperture optimization using an inverse form of back‐projection
title_sort direct aperture optimization using an inverse form of back‐projection
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875482/
https://www.ncbi.nlm.nih.gov/pubmed/24710439
http://dx.doi.org/10.1120/jacmp.v15i2.4545
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