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A new plan quality index for dose painting radiotherapy

Dose painting radiotherapy is considered a promising radiotherapy technology that enables more targeted dose delivery to tumor rich regions while saving critical normal tissues. Obviously, dose painting planning would be more complicated and hard to be evaluated with current plan quality index syste...

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Detalles Bibliográficos
Autores principales: Park, Yang‐Kyun, Park, Soyeon, Wu, Hong‐Gyun, Kim, Siyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875497/
https://www.ncbi.nlm.nih.gov/pubmed/25207424
http://dx.doi.org/10.1120/jacmp.v15i4.4941
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author Park, Yang‐Kyun
Park, Soyeon
Wu, Hong‐Gyun
Kim, Siyong
author_facet Park, Yang‐Kyun
Park, Soyeon
Wu, Hong‐Gyun
Kim, Siyong
author_sort Park, Yang‐Kyun
collection PubMed
description Dose painting radiotherapy is considered a promising radiotherapy technology that enables more targeted dose delivery to tumor rich regions while saving critical normal tissues. Obviously, dose painting planning would be more complicated and hard to be evaluated with current plan quality index systems that were developed under the paradigm of uniform dose prescription. In this study, we introduce a new plan quality index, named “index of achievement (IOA)” that assesses how close the planned dose distribution is to the prescribed one in a dose painting radiotherapy plan. By using voxel‐based comparison between planned and prescribed dose distributions in its formulation, the index allows for a single‐value evaluation regardless of the number of prescribed dose levels, which cannot be achieved with the conventional indices such as conventional homogeneity index. Benchmark calculations using patient data demonstrated feasibility of the index not only for contour‐based dose painting plans, but also for dose painting by numbers plans. Also, it was shown that there is strong correlation between the new index and conventional indices, which indicates a potential of the new index as an alternative to conventional ones in general radiotherapy plan evaluation. PACS number: 87.55.D‐
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spelling pubmed-58754972018-04-02 A new plan quality index for dose painting radiotherapy Park, Yang‐Kyun Park, Soyeon Wu, Hong‐Gyun Kim, Siyong J Appl Clin Med Phys Radiation Oncology Physics Dose painting radiotherapy is considered a promising radiotherapy technology that enables more targeted dose delivery to tumor rich regions while saving critical normal tissues. Obviously, dose painting planning would be more complicated and hard to be evaluated with current plan quality index systems that were developed under the paradigm of uniform dose prescription. In this study, we introduce a new plan quality index, named “index of achievement (IOA)” that assesses how close the planned dose distribution is to the prescribed one in a dose painting radiotherapy plan. By using voxel‐based comparison between planned and prescribed dose distributions in its formulation, the index allows for a single‐value evaluation regardless of the number of prescribed dose levels, which cannot be achieved with the conventional indices such as conventional homogeneity index. Benchmark calculations using patient data demonstrated feasibility of the index not only for contour‐based dose painting plans, but also for dose painting by numbers plans. Also, it was shown that there is strong correlation between the new index and conventional indices, which indicates a potential of the new index as an alternative to conventional ones in general radiotherapy plan evaluation. PACS number: 87.55.D‐ John Wiley and Sons Inc. 2014-07-08 /pmc/articles/PMC5875497/ /pubmed/25207424 http://dx.doi.org/10.1120/jacmp.v15i4.4941 Text en © 2014 The Authors. This is an open access article under the terms of the http://creativecommons.org/licenses/by/3.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Park, Yang‐Kyun
Park, Soyeon
Wu, Hong‐Gyun
Kim, Siyong
A new plan quality index for dose painting radiotherapy
title A new plan quality index for dose painting radiotherapy
title_full A new plan quality index for dose painting radiotherapy
title_fullStr A new plan quality index for dose painting radiotherapy
title_full_unstemmed A new plan quality index for dose painting radiotherapy
title_short A new plan quality index for dose painting radiotherapy
title_sort new plan quality index for dose painting radiotherapy
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875497/
https://www.ncbi.nlm.nih.gov/pubmed/25207424
http://dx.doi.org/10.1120/jacmp.v15i4.4941
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