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Bremsstrahlung dose of (165)Dy in radiosynovectomy

There has been an increased interest in (165)Dy radiossynovectomy, which emits relatively high‐energy (> 1 MeV) beta rays. The production of in vivo bremsstrachlung radiation hazards warrants evaluation. The bremsstrahlung component of the decay scheme of (165)Dy has been traditionally ignored in...

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Detalles Bibliográficos
Autor principal: Manjunatha, H.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875505/
https://www.ncbi.nlm.nih.gov/pubmed/25207401
http://dx.doi.org/10.1120/jacmp.v15i4.4746
Descripción
Sumario:There has been an increased interest in (165)Dy radiossynovectomy, which emits relatively high‐energy (> 1 MeV) beta rays. The production of in vivo bremsstrachlung radiation hazards warrants evaluation. The bremsstrahlung component of the decay scheme of (165)Dy has been traditionally ignored in internal dosimetry calculations. We have estimated the bremsstrahlung dose of (165)Dy distributed in muscle and bone to body by various internal organs (adrenals, brain, breasts, gallbladder wall, LLI wall, small intestine, stomach, ULI wall, heart wall, kidneys, liver, lungs, muscle, ovaries, pancreas, red marrow, bone surfaces, skin, spleen, testes, thymus, thyroid, urine bladder wall, uterus, fetus, placenta, and total body) during radiosynovictomy. In the present study, muscle and bone are considered to be source organs. These estimated values show that the bremsstrahlung radiation absorbed dose contribution from an organ to itself is very small compared to that originating from the beta source. However, contribution to other organs is not always negligible, especially when large amounts of (165)Dy may be involved, such as in therapy applications. Hence the component of the total dose due to bremsstrahlung dose should be considered in radiosynovictomy or other therapy applications. PACS numbers: 34.80.‐i, 78.70.‐g, 33.20.Rm, 34.50.Bw