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Modelling the Functional Comorbidity Index as a predictor of health-related quality of life in patients with glenoid labrum disorders

BACKGROUND/AIM: Health-related quality of life (HRQoL) is increasingly assessed within orthopaedic research. For those patients presenting with glenoid labral pathologies, there is little information on how baseline comorbidities affect long-term outcomes and HRQoL. This study aimed to investigate a...

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Autores principales: Zughaib, Marc, Gagnier, Joel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Open Sport & Exercise Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875632/
https://www.ncbi.nlm.nih.gov/pubmed/29616143
http://dx.doi.org/10.1136/bmjsem-2016-000167
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author Zughaib, Marc
Gagnier, Joel J
author_facet Zughaib, Marc
Gagnier, Joel J
author_sort Zughaib, Marc
collection PubMed
description BACKGROUND/AIM: Health-related quality of life (HRQoL) is increasingly assessed within orthopaedic research. For those patients presenting with glenoid labral pathologies, there is little information on how baseline comorbidities affect long-term outcomes and HRQoL. This study aimed to investigate a model, including baseline comorbidities and demographics, to predict change in 2-year HRQoL scores in adult patients with glenoid labral tears or degenerations. METHODS: Participants provided Functional Comorbidity Index (FCI) scores and self-completed the Western Ontario Rotator Cuff (WORC) index at 6, 12 and 24 months. Univariable and multivariable linear regressions were performed to assess predictive quality of baseline comorbidities and demographics on the primary outcome measure of interest (change in WORC score). RESULTS: Multivariate regression with a continuous scaled FCI (β=617.8, p=0.042), age (by decade) (β=297, p<0.01), surgical group (β=−476.69, p<0.01) and an interaction term between FCI and age (β=−103.65, p=0.03) were significant predictors of change in WORC scores at 2-year follow-up (r(2)=0.293858). Multivariate regression with FCI scaled categorically reported only patients with three comorbidities (β=−454.06, p=0.057) and age (by decade) (β=156.87, p=0.04) as the only significant predictors of change in WORC scores at 2-year follow-up (r(2)=0.1279). CONCLUSION: The continuous FCI model is better suited to predict future WORC and HRQoL scores among this patient population. Patients reporting with higher numbers of baseline comorbidities improved significantly more than patients with fewer comorbidities. This information on expected change in HRQoL scores among patients with a wide range of FCI scores at baseline may help guide treatment decisions based on these criteria.
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spelling pubmed-58756322018-04-03 Modelling the Functional Comorbidity Index as a predictor of health-related quality of life in patients with glenoid labrum disorders Zughaib, Marc Gagnier, Joel J BMJ Open Sport Exerc Med Original Article BACKGROUND/AIM: Health-related quality of life (HRQoL) is increasingly assessed within orthopaedic research. For those patients presenting with glenoid labral pathologies, there is little information on how baseline comorbidities affect long-term outcomes and HRQoL. This study aimed to investigate a model, including baseline comorbidities and demographics, to predict change in 2-year HRQoL scores in adult patients with glenoid labral tears or degenerations. METHODS: Participants provided Functional Comorbidity Index (FCI) scores and self-completed the Western Ontario Rotator Cuff (WORC) index at 6, 12 and 24 months. Univariable and multivariable linear regressions were performed to assess predictive quality of baseline comorbidities and demographics on the primary outcome measure of interest (change in WORC score). RESULTS: Multivariate regression with a continuous scaled FCI (β=617.8, p=0.042), age (by decade) (β=297, p<0.01), surgical group (β=−476.69, p<0.01) and an interaction term between FCI and age (β=−103.65, p=0.03) were significant predictors of change in WORC scores at 2-year follow-up (r(2)=0.293858). Multivariate regression with FCI scaled categorically reported only patients with three comorbidities (β=−454.06, p=0.057) and age (by decade) (β=156.87, p=0.04) as the only significant predictors of change in WORC scores at 2-year follow-up (r(2)=0.1279). CONCLUSION: The continuous FCI model is better suited to predict future WORC and HRQoL scores among this patient population. Patients reporting with higher numbers of baseline comorbidities improved significantly more than patients with fewer comorbidities. This information on expected change in HRQoL scores among patients with a wide range of FCI scores at baseline may help guide treatment decisions based on these criteria. BMJ Open Sport & Exercise Medicine 2017-02-08 /pmc/articles/PMC5875632/ /pubmed/29616143 http://dx.doi.org/10.1136/bmjsem-2016-000167 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) [year]. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Original Article
Zughaib, Marc
Gagnier, Joel J
Modelling the Functional Comorbidity Index as a predictor of health-related quality of life in patients with glenoid labrum disorders
title Modelling the Functional Comorbidity Index as a predictor of health-related quality of life in patients with glenoid labrum disorders
title_full Modelling the Functional Comorbidity Index as a predictor of health-related quality of life in patients with glenoid labrum disorders
title_fullStr Modelling the Functional Comorbidity Index as a predictor of health-related quality of life in patients with glenoid labrum disorders
title_full_unstemmed Modelling the Functional Comorbidity Index as a predictor of health-related quality of life in patients with glenoid labrum disorders
title_short Modelling the Functional Comorbidity Index as a predictor of health-related quality of life in patients with glenoid labrum disorders
title_sort modelling the functional comorbidity index as a predictor of health-related quality of life in patients with glenoid labrum disorders
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875632/
https://www.ncbi.nlm.nih.gov/pubmed/29616143
http://dx.doi.org/10.1136/bmjsem-2016-000167
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