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Pluripotency gene network dynamics: System views from parametric analysis
Multiple experimental data demonstrated that the core gene network orchestrating self-renewal and differentiation of mouse embryonic stem cells involves activity of Oct4, Sox2 and Nanog genes by means of a number of positive feedback loops among them. However, recent studies indicated that the archi...
Autores principales: | Akberdin, Ilya R., Omelyanchuk, Nadezda A., Fadeev, Stanislav I., Leskova, Natalya E., Oschepkova, Evgeniya A., Kazantsev, Fedor V., Matushkin, Yury G., Afonnikov, Dmitry A., Kolchanov, Nikolay A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875786/ https://www.ncbi.nlm.nih.gov/pubmed/29596533 http://dx.doi.org/10.1371/journal.pone.0194464 |
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