Low SOX2 expression marks a distinct subset of adenoid cystic carcinoma of the head and neck and is associated with an advanced tumor stage

INTRODUCTION: The transcription factor SOX2 has been identified as a lineage survival oncogene in squamous cell carcinoma and copy number gain is a common event in several human malignancies including head and neck cancer. However, the regulation and function of SOX2 during carcinogenesis as well as...

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Detalles Bibliográficos
Autores principales: Thierauf, Julia, Weissinger, Stephanie E., Veit, Johannes A., Affolter, Annette, Laureano, Natalia K., Beutner, Dirk, Heiduschka, Gregor, Kadletz, Lorenz, Meyer, Moritz, Quaas, Alexander, Plinkert, Peter, Hoffmann, Thomas K., Hess, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875788/
https://www.ncbi.nlm.nih.gov/pubmed/29596469
http://dx.doi.org/10.1371/journal.pone.0194989

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