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Hic-5 Regulates Fibrillar Adhesion Formation to Control Tumor Extracellular Matrix Remodeling through Interaction with Tensin1

The linearization of the stromal extracellular matrix (ECM) by cancer associated fibroblasts (CAFs) facilitates tumor cell growth and metastasis. However, the mechanism by which the ECM is remodeled is not fully understood. Hic-5 (TGFβ1i1), a focal adhesion scaffold protein, has previously been repo...

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Detalles Bibliográficos
Autores principales: Goreczny, Gregory J., Forsythe, Ian J., Turner, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876083/
https://www.ncbi.nlm.nih.gov/pubmed/29348458
http://dx.doi.org/10.1038/s41388-017-0074-2