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Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients

OBJECTIVE: Epigenetic modifications have previously been associated with rheumatoid arthritis (RA). In this study, we aimed to determine whether differential DNA methylation in peripheral blood cell subpopulations is associated with any of 4 clinical outcomes among RA patients. METHODS: Peripheral b...

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Detalles Bibliográficos
Autores principales: Mok, Amanda, Rhead, Brooke, Holingue, Calliope, Shao, Xiaorong, Quach, Hong L., Quach, Diana, Sinclair, Elizabeth, Graf, Jonathan, Imboden, John, Link, Thomas, Harrison, Ruby, Chernitskiy, Vladimir, Barcellos, Lisa F., Criswell, Lindsey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876118/
https://www.ncbi.nlm.nih.gov/pubmed/29287311
http://dx.doi.org/10.1002/art.40408