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IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes
Immunosuppressive regulatory T lymphocytes (Treg) expressing the transcription factor Foxp3 play a vital role in the maintenance of tolerance of the immune-system to self and innocuous non-self. Most Treg that are critical for the maintenance of tolerance to self, develop as an independent T-cell li...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876181/ https://www.ncbi.nlm.nih.gov/pubmed/28540653 http://dx.doi.org/10.1007/s13238-017-0425-3 |