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IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes

Immunosuppressive regulatory T lymphocytes (Treg) expressing the transcription factor Foxp3 play a vital role in the maintenance of tolerance of the immune-system to self and innocuous non-self. Most Treg that are critical for the maintenance of tolerance to self, develop as an independent T-cell li...

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Detalles Bibliográficos
Autores principales:	Apert, Cécile, Romagnoli, Paola, van Meerwijk, Joost P. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876181/ https://www.ncbi.nlm.nih.gov/pubmed/28540653 http://dx.doi.org/10.1007/s13238-017-0425-3

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