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Deciphering the Dichotomous Effects of PGC-1α on Tumorigenesis and Metastasis
Metabolic reprogramming confers cancer cells the ability to grow and survive under nutrient-depleted or stressful microenvironments. The amplification of oncogenes, the loss of tumor suppressors, as well as context- and lineage-specific determinants can converge and profoundly affect the metabolic s...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876244/ https://www.ncbi.nlm.nih.gov/pubmed/29629336 http://dx.doi.org/10.3389/fonc.2018.00075 |