SIRT6 facilitates directional telomere movement upon oxidative damage

Oxidative damage to telomeres leads to telomere attrition and genomic instability, resulting in poor cell viability. Telomere dynamics contribute to the maintenance of telomere integrity; however, whether oxidative damage induces telomere movement and how telomere mobility is regulated remain poorly...

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Detalles Bibliográficos
Autores principales: Gao, Ying, Tan, Jun, Jin, Jingyi, Ma, Hongqiang, Chen, Xiukai, Leger, Brittany, Xu, Jianquan, Spagnol, Stephen T., Dahl, Kris Noel, Levine, Arthur S., Liu, Yang, Lan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876328/
https://www.ncbi.nlm.nih.gov/pubmed/29599436
http://dx.doi.org/10.1038/s41598-018-23602-0

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