Hidden genomic MHC disparity between HLA-matched sibling pairs in hematopoietic stem cell transplantation

Matching classical HLA alleles between donor and recipient is an important factor in avoiding adverse immunological effects in HSCT. Siblings with no differences in HLA alleles, either due to identical-by-state or identical-by-descent status, are considered to be optimal donors. We carried out a ret...

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Detalles Bibliográficos
Autores principales: Koskela, Satu, Ritari, Jarmo, Hyvärinen, Kati, Kwan, Tony, Niittyvuopio, Riitta, Itälä-Remes, Maija, Pastinen, Tomi, Partanen, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876349/
https://www.ncbi.nlm.nih.gov/pubmed/29599509
http://dx.doi.org/10.1038/s41598-018-23682-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876349/
https://www.ncbi.nlm.nih.gov/pubmed/29599509
http://dx.doi.org/10.1038/s41598-018-23682-y

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