Cargando…
No perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part
High frequency electrical conditioning stimulation (HFS) is an experimental method to induce increased mechanical pinprick sensitivity in the unconditioned surrounding skin (secondary hyperalgesia). Secondary hyperalgesia is thought to be the result of central sensitization, i.e. increased responsiv...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876401/ https://www.ncbi.nlm.nih.gov/pubmed/29599492 http://dx.doi.org/10.1038/s41598-018-23135-6 |
_version_ | 1783310506522574848 |
---|---|
author | Torta, D. M. Filbrich, L. Van Den Broeke, E. N. Legrain, V. |
author_facet | Torta, D. M. Filbrich, L. Van Den Broeke, E. N. Legrain, V. |
author_sort | Torta, D. M. |
collection | PubMed |
description | High frequency electrical conditioning stimulation (HFS) is an experimental method to induce increased mechanical pinprick sensitivity in the unconditioned surrounding skin (secondary hyperalgesia). Secondary hyperalgesia is thought to be the result of central sensitization, i.e. increased responsiveness of nociceptive neurons in the central nervous system. Vibrotactile and visual stimuli presented in the area of secondary hyperalgesia also elicit enhanced brain responses, a finding that cannot be explained by central sensitization as it is currently defined. HFS may recruit attentional processes, which in turn affect the processing of all stimuli. In this study we have investigated whether HFS induces perceptual biases towards stimuli presented onto the sensitized arm by using Temporal Order Judgment (TOJ) tasks. In TOJ tasks, stimuli are presented in rapid succession on either arm, and participants have to indicate their perceived order. In case of a perceptual bias, the stimuli presented on the attended side are systematically reported as occurring first. Participants performed a tactile and a visual TOJ task before and after HFS. Analyses of participants’ performance did not reveal any prioritization of the visual and tactile stimuli presented onto the sensitized arm. Our results provide therefore no evidence for a perceptual bias towards tactile and visual stimuli presented onto the sensitized arm. |
format | Online Article Text |
id | pubmed-5876401 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-58764012018-04-02 No perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part Torta, D. M. Filbrich, L. Van Den Broeke, E. N. Legrain, V. Sci Rep Article High frequency electrical conditioning stimulation (HFS) is an experimental method to induce increased mechanical pinprick sensitivity in the unconditioned surrounding skin (secondary hyperalgesia). Secondary hyperalgesia is thought to be the result of central sensitization, i.e. increased responsiveness of nociceptive neurons in the central nervous system. Vibrotactile and visual stimuli presented in the area of secondary hyperalgesia also elicit enhanced brain responses, a finding that cannot be explained by central sensitization as it is currently defined. HFS may recruit attentional processes, which in turn affect the processing of all stimuli. In this study we have investigated whether HFS induces perceptual biases towards stimuli presented onto the sensitized arm by using Temporal Order Judgment (TOJ) tasks. In TOJ tasks, stimuli are presented in rapid succession on either arm, and participants have to indicate their perceived order. In case of a perceptual bias, the stimuli presented on the attended side are systematically reported as occurring first. Participants performed a tactile and a visual TOJ task before and after HFS. Analyses of participants’ performance did not reveal any prioritization of the visual and tactile stimuli presented onto the sensitized arm. Our results provide therefore no evidence for a perceptual bias towards tactile and visual stimuli presented onto the sensitized arm. Nature Publishing Group UK 2018-03-29 /pmc/articles/PMC5876401/ /pubmed/29599492 http://dx.doi.org/10.1038/s41598-018-23135-6 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Torta, D. M. Filbrich, L. Van Den Broeke, E. N. Legrain, V. No perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part |
title | No perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part |
title_full | No perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part |
title_fullStr | No perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part |
title_full_unstemmed | No perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part |
title_short | No perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part |
title_sort | no perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876401/ https://www.ncbi.nlm.nih.gov/pubmed/29599492 http://dx.doi.org/10.1038/s41598-018-23135-6 |
work_keys_str_mv | AT tortadm noperceptualprioritizationofnonnociceptivevibrotactileandvisualstimulipresentedonasensitizedbodypart AT filbrichl noperceptualprioritizationofnonnociceptivevibrotactileandvisualstimulipresentedonasensitizedbodypart AT vandenbroekeen noperceptualprioritizationofnonnociceptivevibrotactileandvisualstimulipresentedonasensitizedbodypart AT legrainv noperceptualprioritizationofnonnociceptivevibrotactileandvisualstimulipresentedonasensitizedbodypart |