Cargando…

High density of CD68+ tumor-associated macrophages predicts a poor prognosis in gastric cancer mediated by IL-6 expression

The aim of the present study was to explore the potential role of cluster of differentiation CD68+ tumor-associated macrophages (TAMs) induced by interleukin (IL)-6 in the progression of gastric cancer (GC) and patient prognosis. The expression levels of IL-6 and CD68 were detected by immunohistoche...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Chong-Yu, Fu, Xiao-Long, Duan, Wei, Yu, Pei-Wu, Zhao, Yong-Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876426/ https://www.ncbi.nlm.nih.gov/pubmed/29616104 http://dx.doi.org/10.3892/ol.2018.8119

Ejemplares similares

High Counts of CD68+ and CD163+ Macrophages in Mantle Cell Lymphoma Are Associated With Inferior Prognosis
por: Li, Philippa, et al.
Publicado: (2021)

Bone marrow expression of CD68/CD163 macrophages, IL‐17 and FOXP3 cells in aplastic anemia and their relation to prognosis
por: Vaht, Krista, et al.
Publicado: (2022)

The Expression and Relationship of CD68-Tumor-Associated Macrophages and Microvascular Density With the Prognosis of Patients With Laryngeal Squamous Cell Carcinoma
por: Sun, Shujun, et al.
Publicado: (2016)

PD-1(+)CD8(+) T Cells Proximal to PD-L1(+)CD68(+) Macrophages Are Associated with Poor Prognosis in Pancreatic Ductal Adenocarcinoma Patients
por: Yang, Xiaobao, et al.
Publicado: (2023)

Tumor-infiltrating CD8+ T cells combined with tumor-associated CD68+ macrophages predict postoperative prognosis and adjuvant chemotherapy benefit in resected gastric cancer
por: Lu, Jun, et al.
Publicado: (2019)

CD45(+)CD33(low)CD11b(dim) myeloid-derived suppressor cells suppress CD8(+) T cell activity via the IL-6/IL-8-arginase I axis in human gastric cancer
por: Mao, Fang-yuan, et al.
Publicado: (2018)

Integration of OV6 expression and CD68(+) tumor-associated macrophages with clinical features better predicts the prognosis of patients with hepatocellular carcinoma
por: Wang, Ming-Da, et al.
Publicado: (2022)

Relationship of Tumor-Associated Macrophage Population Detected by CD68 PG-M1, CD68 KP1, and CD163 with Latent EBV Infection and Prognosis in Classical Hodgkin Lymphoma
por: Mavili, Hanife Seda, et al.
Publicado: (2021)

Elevated CD163(+)/CD68(+) Ratio at Tumor Invasive Front is Closely Associated with Aggressive Phenotype and Poor Prognosis in Colorectal Cancer
por: Yang, Chaogang, et al.
Publicado: (2019)

High CD204(+) tumor-infiltrating macrophage density predicts a poor prognosis in patients with urothelial cell carcinoma of the bladder
por: Wang, Bo, et al.
Publicado: (2015)

High Infiltration of CD68(+)/CD163(−) Macrophages Is an Adverse Prognostic Factor after Neoadjuvant Chemotherapy in Esophageal and Gastric Adenocarcinoma
por: Svensson, Maria C., et al.
Publicado: (2022)

LINC01094 Predicts Poor Prognosis in Patients With Gastric Cancer and is Correlated With EMT and Macrophage Infiltration
por: Ye, Yuanchun, et al.
Publicado: (2022)

The Clinical Significance of the CD163+ and CD68+ Macrophages in Patients with Hepatocellular Carcinoma
por: Kong, Ling-Qun, et al.
Publicado: (2013)

Upregulation of FGD6 Predicts Poor Prognosis in Gastric Cancer
por: Zeng, Jianmin, et al.
Publicado: (2021)

Enrichment of Murine CD68(+)CCR2(+) and CD68(+)CD206(+) Lung Macrophages in Acute Pancreatitis-Associated Acute Lung Injury
por: Akbarshahi, Hamid, et al.
Publicado: (2012)

High-level of intratumoral GITR+ CD4 T cells associate with poor prognosis in gastric cancer
por: Ke, Shouyu, et al.
Publicado: (2022)

Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis
por: Chang, Yu-Chan, et al.
Publicado: (2017)

CD163 versus CD68 in tumor associated macrophages of classical hodgkin lymphoma
por: Harris, Jonathan A, et al.
Publicado: (2012)

The number and localization of CD68+ and CD163+ macrophages in different stages of cutaneous melanoma
por: Salmi, Satu, et al.
Publicado: (2019)

Prophylaxis of decidual CD68(+)/CD163(+) macrophage disbalance in extracorporeal fertilized women
por: Likhachov, Volodymyr, et al.
Publicado: (2023)

Prognostic value of PD‑L1 expression and CD68 macrophages in tumor nest of patients with primary gastric cancer
por: Zou, Yunlian, et al.
Publicado: (2023)

Low expression of IL6R predicts poor prognosis for lung adenocarcinoma
por: Sun, Gaofeng, et al.
Publicado: (2021)

Decrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic Rats
por: Cascão, Rita, et al.
Publicado: (2015)

High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus
por: Seminerio, Imelda, et al.
Publicado: (2018)

Immunoscore Combining CD8, FoxP3, and CD68-Positive Cells Density and Distribution Predicts the Prognosis of Head and Neck Cancer Patients
por: Furgiuele, Sonia, et al.
Publicado: (2022)

Role of CD68 in tumor immunity and prognosis prediction in pan-cancer
por: Zhang, Jingwei, et al.
Publicado: (2022)

High Infiltration of Tumor-Associated Macrophages Influences Poor Prognosis in Human Gastric Cancer Patients, Associates With the Phenomenon of EMT
por: Zhang, Jia, et al.
Publicado: (2016)

CD68- and CD163-positive tumor-associated macrophages in triple negative cancer of the breast
por: Jamiyan, Tsengelmaa, et al.
Publicado: (2020)

CD44v6 overexpression related to metastasis and poor prognosis of colorectal cancer: A meta-analysis
por: Wang, Ji-Lin, et al.
Publicado: (2016)

Expression of CD133 in the cytoplasm is associated with cancer progression and poor prognosis in gastric cancer
por: Hashimoto, Kousuke, et al.
Publicado: (2013)

Overexpression of CD55 correlates with tumor progression and poor prognosis in gastric stromal tumors
por: Yin, Xiaonan, et al.
Publicado: (2019)

DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation
por: Lai, Ssu-Chuan, et al.
Publicado: (2019)

Regional differences in the density of Langerhans cells, CD8-positive T lymphocytes and CD68-positive macrophages: a preliminary study using elderly donated cadavers
por: Omine, Yuya, et al.
Publicado: (2015)

The role of CD68+ macrophage in classical Hodgkin lymphoma patients from Egypt
por: Mohamed, Osama, et al.
Publicado: (2020)

CD44 is a potential immunotherapeutic target and affects macrophage infiltration leading to poor prognosis
por: Liu, Shuangqing, et al.
Publicado: (2023)

Increased PD-1-positive macrophages in the tissue of gastric cancer are closely associated with poor prognosis in gastric cancer patients
por: Kono, Yusuke, et al.
Publicado: (2020)

Expression of LOX Suggests Poor Prognosis in Gastric Cancer
por: Zhu, Jinfeng, et al.
Publicado: (2021)

Omental Macrophagic “Crown-like Structures” Are Associated with Poor Prognosis in Advanced-Stage Serous Ovarian Cancer
por: Liang, Yu-Ling, et al.
Publicado: (2021)

Correction to: DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation
por: Lai, Ssu-Chuan, et al.
Publicado: (2020)

Regulatory T Cells Promote Overexpression of Lgr5 on Gastric Cancer Cells via TGF-beta1 and Confer Poor Prognosis in Gastric Cancer
por: Liu, Xiao-Sun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jtbasdkfc5ph45vsal5dr80n5e