Mutational Analysis of Neuropeptide Y Reveals Unusual Thermal Stability Linked to Higher-Order Self-Association

[Image: see text] Neuropeptide Y (NPY) is a 36-residue peptide, abundant in the central and peripheral nervous system. The peptide interacts with membrane-bound receptors to control processes such as food intake, vasoconstriction, and memory retention. The N-terminal polyproline sequence of NPY fold...

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Detalles Bibliográficos
Autores principales: Quirk, Stephen, Hopkins, Mandi M., Bureau, Hailey, Lusk, Ryan J., Allen, Caley, Hernandez, Rigoberto, Bain, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876621/
https://www.ncbi.nlm.nih.gov/pubmed/29619413
http://dx.doi.org/10.1021/acsomega.7b01949

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