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New Insights into Protein Kinase B/Akt Signaling: Role of Localized Akt Activation and Compartment-Specific Target Proteins for the Cellular Radiation Response

Genetic alterations driving aberrant activation of the survival kinase Protein Kinase B (Akt) are observed with high frequency during malignant transformation and cancer progression. Oncogenic gene mutations coding for the upstream regulators or Akt, e.g., growth factor receptors, RAS and phosphatid...

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Detalles Bibliográficos
Autores principales:	Szymonowicz, Klaudia, Oeck, Sebastian, Malewicz, Nathalie M., Jendrossek, Verena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876653/ https://www.ncbi.nlm.nih.gov/pubmed/29562639 http://dx.doi.org/10.3390/cancers10030078

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