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New Insights into Protein Kinase B/Akt Signaling: Role of Localized Akt Activation and Compartment-Specific Target Proteins for the Cellular Radiation Response
Genetic alterations driving aberrant activation of the survival kinase Protein Kinase B (Akt) are observed with high frequency during malignant transformation and cancer progression. Oncogenic gene mutations coding for the upstream regulators or Akt, e.g., growth factor receptors, RAS and phosphatid...
Autores principales: | Szymonowicz, Klaudia, Oeck, Sebastian, Malewicz, Nathalie M., Jendrossek, Verena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876653/ https://www.ncbi.nlm.nih.gov/pubmed/29562639 http://dx.doi.org/10.3390/cancers10030078 |
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