Cargando…

Association between the DNA methylations of POMC, MC4R, and HNF4A and metabolic profiles in the blood of children aged 7–9 years

BACKGROUND: Proopiomelanocortin (POMC), melanocortin 4 receptor (MC4R), and hepatocyte nuclear factor 4 alpha (HNF4A) are closely associated with weight gain and metabolic traits. In a previous study, we demonstrated associations between the methylations of POMC, MC4R, and HNF4A and metabolic profil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kwon, Eun Jin, You, Young-Ah, Park, Bohyun, Ha, Eun Hee, Kim, Hae Soon, Park, Hyesook, Kim, Young Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877386/ https://www.ncbi.nlm.nih.gov/pubmed/29598821 http://dx.doi.org/10.1186/s12887-018-1104-0

Ejemplares similares

DNA methylations of MC4R and HNF4α are associated with increased triglyceride levels in cord blood of preterm infants
por: Kwon, Eun Jin, et al.
Publicado: (2016)

MC4R and HNF4α promoter methylation at birth contribute to triglyceride levels in childhood: A prospective cohort study
por: Kwon, Eun Jin, et al.
Publicado: (2019)

Maternal Malnutrition Affects Hepatic Metabolism through Decreased Hepatic Taurine Levels and Changes in HNF4A Methylation
por: Du, Ji Eun, et al.
Publicado: (2020)

Trajectory patterns for continuous metabolic syndrome score in childhood and the cardiovascular risk in adolescence
por: Choi, Eun Jeong, et al.
Publicado: (2021)

Association between pre-and postnatal growth and longitudinal trends in serum uric acid levels and blood pressure in children aged 3 to 7 years
por: Park, Bomi, et al.
Publicado: (2020)

25-Hydroxyvitamin D status, metabolic syndrome and insulin resistance in preadolescent child in Korea
por: Kim, Hae Soon, et al.
Publicado: (2013)

Impact of Nucleotide Mutations at the HNF3- and HNF4-Binding Sites in Enhancer 1 on Viral Replication in Patients with Chronic Hepatitis B Virus Infection
por: Cho, Eun-young, et al.
Publicado: (2013)

Blood Pressure Curve for Children Less than 10 Years of Age: Findings from the Ewha Birth and Growth Cohort Study
por: Lee, Hye Ah, et al.
Publicado: (2020)

The association between metabolic components and markers of inflammatory and endothelial dysfunction in adolescents, based on the Ewha Birth and Growth Cohort Study
por: Lee, Hye Ah, et al.
Publicado: (2020)

Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice
por: Tooke, Benjamin P., et al.
Publicado: (2018)

Cohort profile: the Ewha Birth and Growth Study
por: Lee, Hye Ah, et al.
Publicado: (2021)

Effects of Prenatal Growth Status on Subsequent Childhood Renal Function Related to High Blood Pressure
por: Park, Bohyun, et al.
Publicado: (2019)

Prospective association between phthalate exposure in childhood and liver function in adolescence: the Ewha Birth and Growth Cohort Study
por: Lee, Seonhwa, et al.
Publicado: (2023)

Blood pressure trajectory modeling in childhood: birth-cohort study
por: Lee, Jung Won, et al.
Publicado: (2020)

Effect of Urinary Bisphenol A on Androgenic Hormones and Insulin Resistance in Preadolescent Girls: A Pilot Study from the Ewha Birth & Growth Cohort
por: Lee, Hye Ah, et al.
Publicado: (2013)

Long-term effects of the SLC2A9 G844A and SLC22A12 C246T variants on serum uric acid concentrations in children
por: Lee, Hye Ah, et al.
Publicado: (2018)

Effects of Adrenal Androgen Levels on Bone Age Advancement in Prepubertal Children: Using the Ewha Birth and Growth Cohort Study
por: Kwon, Jung Hyun, et al.
Publicado: (2017)

Mir214-3p and Hnf4a/Hnf4α reciprocally regulate Ulk1 expression and autophagy in nonalcoholic hepatic steatosis
por: Lee, Da-Hye, et al.
Publicado: (2020)

Incidence-Based versus Prevalence-Based Approaches on Measuring Disability-Adjusted Life Years for Injury
por: Park, Bohyun, et al.
Publicado: (2019)

Erratum: Correction of the Text in the Article “Funding”: Incidence-Based versus Prevalence-Based Approaches on Measuring Disability-Adjusted Life Years for Injury
por: Park, Bohyun, et al.
Publicado: (2019)

Mendelian Randomization Analysis of the Effect of Maternal Homocysteine During Pregnancy, as Represented by Maternal MTHFR C677T Genotype, on Birth Weight
por: Lee, Hye Ah, et al.
Publicado: (2013)

Crystallization of hepatocyte nuclear factor 4α (HNF4α) in complex with the HNF1α promoter element
por: Lu, Peng, et al.
Publicado: (2008)

Disease-Specific Mortality and Prevalence Trends in Korea, 2002–2015
por: Shin, Yoonhee, et al.
Publicado: (2020)

Differential expression and methylation of integrin subunit alpha 11 and thrombospondin in the amnion of preterm birth
por: Yoo, Jae Young, et al.
Publicado: (2018)

Timing of Onset of Adverse Events With Setmelanotide, an MC4R Agonist, in Patients With Severe Obesity Due to LEPR or POMC Deficiency
por: Clément, Karine, et al.
Publicado: (2021)

Combined effect of folate and adiposity on homocysteine in children at three years of age
por: Cho, Su Jin, et al.
Publicado: (2016)

Combined effects of dietary zinc at 3 years of age and obesity at 7 years of age on the serum uric acid levels of Korean children
por: Lee, Sung Hee, et al.
Publicado: (2020)

HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer
por: Chang, Hae Ryung, et al.
Publicado: (2016)

Which Diet-Related Behaviors in Childhood Influence a Healthier Dietary Pattern? From the Ewha Birth and Growth Cohort
por: Lee, Hye Ah, et al.
Publicado: (2016)

Projection of the Years of Life Lost, Years Lived with Disability, and Disability-Adjusted Life Years in Korea for 2030
por: Park, Bomi, et al.
Publicado: (2018)

Chronic Restraint Stress Decreases the Excitability of Hypothalamic POMC Neuron and Increases Food Intake
por: Ha, Go Eun, et al.
Publicado: (2021)

A study on the factors affecting the follow-up participation in birth cohorts
por: Park, Bohyun, et al.
Publicado: (2016)

Evaluation of MC4R [RS17782313, RS17700633], AGRP [RS3412352] and POMC [RS1042571] polymorphisms with obesity in Northern India
por: Srivastava, Apurva, et al.
Publicado: (2014)

Species-Specific Differences in the Expression of the HNF1A, HNF1B and HNF4A Genes
por: Harries, Lorna W., et al.
Publicado: (2009)

The Effect of Childhood Obesity or Sarcopenic Obesity on Metabolic Syndrome Risk in Adolescence: The Ewha Birth and Growth Study
por: Park, Hyunjin, et al.
Publicado: (2023)

Activation of the ARC(POMC)→MeA Projection Reduces Food Intake
por: Kwon, Eunjin, et al.
Publicado: (2020)

Long-term effects of pro-opiomelanocortin methylation induced in food-restricted dams on metabolic phenotypes in male rat offspring
por: Lee, Sangmi, et al.
Publicado: (2020)

The association between urinary cotinine level and metabolic syndrome profiles among adolescents: findings from the Ewha Birth and growth study
por: Park, Hyunjin, et al.
Publicado: (2023)

Structural insights into the HNF4 biology
por: Beinsteiner, Brice, et al.
Publicado: (2023)

Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation
por: Wang, Ping, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_cn14fir5rrutbdhe3336566f3f