Dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge

BACKGROUND: Systemic inflammation is associated with increased cognitive decline and risk for Alzheimer’s disease. Microglia (MG) activated during systemic inflammation can cause exaggerated neuroinflammatory responses and trigger progressive neurodegeneration. Dimethyl fumarate (DMF) is a FDA-appro...

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Detalles Bibliográficos
Autores principales: Paraiso, Hallel C., Kuo, Ping-Chang, Curfman, Eric T., Moon, Haley J., Sweazey, Robert D., Yen, Jui-Hung, Chang, Fen-Lei, Yu, I-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877396/
https://www.ncbi.nlm.nih.gov/pubmed/29598822
http://dx.doi.org/10.1186/s12974-018-1125-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877396/
https://www.ncbi.nlm.nih.gov/pubmed/29598822
http://dx.doi.org/10.1186/s12974-018-1125-5

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