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Interaction between rpsL and gyrA mutations affects the fitness and dual resistance of Mycobacterium tuberculosis clinical isolates against streptomycin and fluoroquinolones

BACKGROUND: The interaction between different drug-resistant mutations is important to the development of drug resistance and its evolution. In this study, we aimed to reveal the potential relationships between mutations conferring resistance to two important antituberculosis drugs streptomycin (STR...

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Detalles Bibliográficos
Autores principales:	Sun, Honghu, Zeng, Jumei, Li, Song, Liang, Pengkuan, Zheng, Chao, Liu, Yong, Luo, Tao, Rastogi, Nalin, Sun, Qun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877491/ https://www.ncbi.nlm.nih.gov/pubmed/29628767 http://dx.doi.org/10.2147/IDR.S152335

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