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Activation of spinal dorsal horn P2Y(13) receptors can promote the expression of IL-1β and IL-6 in rats with diabetic neuropathic pain

OBJECTIVE: The dorsal horn P2Y(13) receptor is involved in the development of pain behavior induced by peripheral nerve injury. It is unclear whether the expression of proinflammatory cytokines interleukin (IL)-1β and IL-6 at the spinal dorsal horn are influenced after the activation of P2Y(13) rece...

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Detalles Bibliográficos
Autores principales: Zhou, Rui, Xu, Tao, Liu, XiaoHong, Chen, YuanShou, Kong, DeYing, Tian, Hong, Yue, Mingxia, Huang, Dujuan, Zeng, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877493/
https://www.ncbi.nlm.nih.gov/pubmed/29628771
http://dx.doi.org/10.2147/JPR.S154437