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Impaired CD27(+)IgD(+) B Cells With Altered Gene Signature in Rheumatoid Arthritis
Natural antibodies, particularly natural IgM, are proved to play indispensable roles in the immune defenses against common infections. More recently, the protective roles of these natural IgM were also recognized in autoimmune diseases. They are mainly produced by B-1 and innate-like B cells (ILBs)....
Autores principales: | Hu, Fanlei, Zhang, Wei, Shi, Lianjie, Liu, Xu, Jia, Yuan, Xu, Liling, Zhu, Huaqun, Li, Yingni, Xu, Dakang, Lu, Liwei, Qiu, Xiaoyan, Liu, Wanli, Qiao, Junjie, Wang, Yongfu, Li, Zhanguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877504/ https://www.ncbi.nlm.nih.gov/pubmed/29628928 http://dx.doi.org/10.3389/fimmu.2018.00626 |
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