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TrkB-Target Galectin-1 Impairs Immune Activation and Radiation Responses in Neuroblastoma: Implications for Tumour Therapy

Galectin-1 (Gal-1) has been described to promote tumour growth by inducing angiogenesis and to contribute to the tumour immune escape. We had previously identified up-regulation of Gal-1 in preclinical models of aggressive neuroblastoma (NB), the most common extracranial tumour of childhood. While G...

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Detalles Bibliográficos
Autores principales: Batzke, Katharina, Büchel, Gabriele, Hansen, Wiebke, Schramm, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877579/
https://www.ncbi.nlm.nih.gov/pubmed/29498681
http://dx.doi.org/10.3390/ijms19030718