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Inhibition of Late and Early Phases of Cancer Metastasis by the NF-κB Inhibitor DHMEQ Derived from Microbial Bioactive Metabolite Epoxyquinomicin: A Review

We previously designed and synthesized dehydroxyepoxyquinomicin (DHMEQ) as an inhibitor of NF-κB based on the structure of microbial secondary metabolite epoxyquinomicin C. DHMEQ showed anti-inflammatory and anticancer activity in various in vivo disease models without toxicity. On the other hand, t...

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Detalles Bibliográficos
Autores principales:	Lin, Yinzhi, Ukaji, Tamami, Koide, Naoki, Umezawa, Kazuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877590/ https://www.ncbi.nlm.nih.gov/pubmed/29510517 http://dx.doi.org/10.3390/ijms19030729

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