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SK-216, a Novel Inhibitor of Plasminogen Activator Inhibitor-1, Suppresses Lung Metastasis of Human Osteosarcoma
Lung metastasis constitutes the leading cause of the death in patients with osteosarcoma. We have previously reported that plasminogen activator inhibitor-1 (PAI-1) regulates the invasion and lung metastasis of osteosarcoma cells in a mouse model and as well as in clinical samples. In the present st...
Autores principales: | Tsuge, Minori, Osaki, Mitsuhiko, Sasaki, Ryo, Hirahata, Mio, Okada, Futoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877597/ https://www.ncbi.nlm.nih.gov/pubmed/29510576 http://dx.doi.org/10.3390/ijms19030736 |
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