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Structural Biology of the TNFα Antagonists Used in the Treatment of Rheumatoid Arthritis

The binding of the tumor necrosis factor α (TNFα) to its cognate receptor initiates many immune and inflammatory processes. The drugs, etanercept (Enbrel(®)), infliximab (Remicade(®)), adalimumab (Humira(®)), certolizumab-pegol (Cimzia(®)), and golimumab (Simponi(®)), are anti-TNFα agents. These dru...

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Detalles Bibliográficos
Autores principales:	Lim, Heejin, Lee, Sang Hyung, Lee, Hyun Tae, Lee, Jee Un, Son, Ji Young, Shin, Woori, Heo, Yong-Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877629/ https://www.ncbi.nlm.nih.gov/pubmed/29518978 http://dx.doi.org/10.3390/ijms19030768

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