Cell-Penetrating Function of the Poly(ADP-Ribose) (PAR)-Binding Motif Derived from the PAR-Dependent E3 Ubiquitin Ligase Iduna

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates cellular responses such as proteasomal degradation and DNA repair upon interaction with its substrate. We identified a highly cationic region within the PAR-binding motif of Iduna; the region was similar among various spe...

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Detalles Bibliográficos
Autores principales: Koo, Ja-Hyun, Yoon, Heeseok, Kim, Won-Ju, Cha, Donghun, Choi, Je-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877640/
https://www.ncbi.nlm.nih.gov/pubmed/29518031
http://dx.doi.org/10.3390/ijms19030779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877640/
https://www.ncbi.nlm.nih.gov/pubmed/29518031
http://dx.doi.org/10.3390/ijms19030779

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