Cargando…

Type 1 Diabetes and Its Multi-Factorial Pathogenesis: The Putative Role of NK Cells

Type 1 diabetes (T1D) affects millions of people worldwide and is the prevalent form of all pediatric diabetes diagnoses. T1D is recognized to have an autoimmune etiology, since failure in specific self-tolerance mechanisms triggers immune reactions towards self-antigens and causes disease onset. Am...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marca, Valeria La, Gianchecchi, Elena, Fierabracci, Alessandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877655/ https://www.ncbi.nlm.nih.gov/pubmed/29534427 http://dx.doi.org/10.3390/ijms19030794

Ejemplares similares

Recent Advances on Microbiota Involvement in the Pathogenesis of Autoimmunity
por: Gianchecchi, Elena, et al.
Publicado: (2019)

Insights on the Effects of Resveratrol and Some of Its Derivatives in Cancer and Autoimmunity: A Molecule with a Dual Activity
por: Gianchecchi, Elena, et al.
Publicado: (2020)

Inhibitory Receptors and Pathways of Lymphocytes: The Role of PD-1 in Treg Development and Their Involvement in Autoimmunity Onset and Cancer Progression
por: Gianchecchi, Elena, et al.
Publicado: (2018)

Identification of GAD65 AA 114-122 reactive 'memory-like' NK cells in newly diagnosed Type 1 diabetic patients by HLA-class I pentamers
por: Perri, Valentina, et al.
Publicado: (2017)

Insights into the Diagnostic Potential of Extracellular Vesicles and Their miRNA Signature from Liquid Biopsy as Early Biomarkers of Diabetic Micro/Macrovascular Complications
por: La Marca, Valeria, et al.
Publicado: (2017)

Sialic Acid-Siglec Axis in Human Immune Regulation, Involvement in Autoimmunity and Cancer and Potential Therapeutic Treatments
por: Gianchecchi, Elena, et al.
Publicado: (2021)

Altered B Cell Homeostasis and Toll-Like Receptor 9-Driven Response in Type 1 Diabetes Carriers of the C1858T PTPN22 Allelic Variant: Implications in the Disease Pathogenesis
por: Gianchecchi, Elena, et al.
Publicado: (2014)

Natural Killer Cells: Potential Biomarkers and Therapeutic Target in Autoimmune Diseases?
por: Gianchecchi, Elena, et al.
Publicado: (2021)

Advances in Immunotherapeutic Approaches to Type 1 Diabetes
por: Cudini, Annamaria, et al.
Publicado: (2023)

Insights into the Role of MicroRNAs in the Onset and Development of Diabetic Neuropathy
por: Simeoli, Raffaele, et al.
Publicado: (2019)

Type 1 Diabetes in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Syndrome (APECED): A “Rare” Manifestation in a “Rare” Disease
por: Fierabracci, Alessandra
Publicado: (2016)

The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic Target
por: Fierabracci, Alessandra, et al.
Publicado: (2016)

Immunotherapy Strategies for the Prevention and Treatment of Distinct Stages of Type 1 Diabetes: An Overview
por: Rapini, Novella, et al.
Publicado: (2020)

Use of short interfering RNA delivered by cationic liposomes to enable efficient down-regulation of PTPN22 gene in human T lymphocytes
por: Perri, Valentina, et al.
Publicado: (2017)

Potential Role of NK Cells in the Pathogenesis of Inflammatory Bowel Disease
por: Yadav, Praveen K., et al.
Publicado: (2011)

Biodiversity and its double-edged role in the pathogenesis of type 1 diabetes
por: Chan, Daniel, et al.
Publicado: (2023)

EBV and the Pathogenesis of NK/T Cell Lymphoma
por: Montes-Mojarro, Ivonne A., et al.
Publicado: (2021)

Identification and functional characterization of CD8(+) T regulatory cells in type 1 diabetes patients
por: Pellegrino, Marsha, et al.
Publicado: (2019)

Deciphering the role of Epstein-Barr virus in the pathogenesis of T and NK cell lymphoproliferations
por: Fox, Christopher P, et al.
Publicado: (2011)

Insights into the Secretome of Mesenchymal Stem Cells and Its Potential Applications
por: Eleuteri, Sharon, et al.
Publicado: (2019)

Identification of putative novel O-glycosylations in the NK killer receptor Ncr1 essential for its activity
por: Glasner, Ariella, et al.
Publicado: (2015)

NK Cells and Type 1 Diabetes
por: Rodacki, Melanie, et al.
Publicado: (2006)

Role of Glucagon and Its Receptor in the Pathogenesis of Diabetes
por: Jia, Yunbo, et al.
Publicado: (2022)

Multi factorial interactions in the pathogenesis pathway of Alzheimer’s disease: a new risk charts for prevention of dementia
por: Licastro, Federico, et al.
Publicado: (2010)

Nasal NK/T-cell lymphoma: epidemiology and pathogenesis
por: Aozasa, Katsuyuki, et al.
Publicado: (2008)

Immune dysregulation in extranodal NK/T cell lymphomas: potential roles in pathogenesis and immunotherapy
por: Polprasert, Chantana, et al.
Publicado: (2021)

Role of pseudohypoxia in the pathogenesis of type 2 diabetes
por: Song, Jing, et al.
Publicado: (2019)

The physiological immunosuppressive network and its putative role in the pathogenesis of autoimmunity: inhibition through signaling, cellular contact, anergy, apoptosis
por: Lorenz, H, et al.
Publicado: (2003)

Editorial: The Role of Natural Killer Cells in Autoimmune Diseases
por: Fierabracci, Alessandra, et al.
Publicado: (2021)

NK Cells in the Pathogenesis of Chronic Obstructive Pulmonary Disease
por: Rao, Yafei, et al.
Publicado: (2021)

The Role of HMGB1 in the Pathogenesis of Type 2 Diabetes
por: Wang, Yanan, et al.
Publicado: (2016)

Autoimmune Addison's Disease as Part of the Autoimmune Polyglandular Syndrome Type 1: Historical Overview and Current Evidence
por: Perniola, Roberto, et al.
Publicado: (2021)

Involvement of Substance P (SP) and Its Related NK1 Receptor in Primary Sjögren’s Syndrome (pSS) Pathogenesis
por: Rosso, Pamela, et al.
Publicado: (2023)

Role of Innate Immunity in the Pathogenesis of Type 1 and Type 2 Diabetes
por: Lee, Myung-Shik
Publicado: (2014)

The role of NK and NKT cells in the pathogenesis and improvement of multiple sclerosis following disease‐modifying therapies
por: Ahmadi, Alireza, et al.
Publicado: (2022)

Cellular Origins and Pathogenesis of Gastrointestinal NK- and T-Cell Lymphoproliferative Disorders
por: Hue, Susan Swee-Shan, et al.
Publicado: (2022)

Detection of GAD65 Autoreactive T-Cells by HLA Class I Tetramers in Type 1 Diabetic Patients
por: Giuliani, Laura, et al.
Publicado: (2009)

Effect of Coxsackievirus B4 Infection on the Thymus: Elucidating Its Role in the Pathogenesis of Type 1 Diabetes
por: Alhazmi, Abdulaziz, et al.
Publicado: (2021)

Roles of Bcl-3 in the Pathogenesis of Murine Type 1 Diabetes
por: Ruan, Qingguo, et al.
Publicado: (2010)

The role of gastrointestinal hormones in the pathogenesis of obesity and type 2 diabetes
por: Adamska, Edyta, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_rmvoekpgm3mk6kg71ntt4k7ku9