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mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome
The mechanistic target of rapamycin complex 1 (mTORC1) coordinates cellular growth and metabolism with environmental inputs to ensure that cells grow only under favourable conditions. When active, mTORC1 stimulates biosynthetic pathways including protein, lipid and nucleotide synthesis and inhibits...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877679/ https://www.ncbi.nlm.nih.gov/pubmed/29534520 http://dx.doi.org/10.3390/ijms19030818 |