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The Role of Post-Translational Modifications on Prion-Like Aggregation and Liquid-Phase Separation of FUS

Subcellular mislocalization and aggregation of the human FUS protein occurs in neurons of patients with subtypes of amyotrophic lateral sclerosis and frontotemporal dementia. FUS is one of several RNA-binding proteins that can functionally self-associate into distinct liquid-phase droplet structures...

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Detalles Bibliográficos
Autores principales:	Rhoads, Shannon N., Monahan, Zachary T., Yee, Debra S., Shewmaker, Frank P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877747/ https://www.ncbi.nlm.nih.gov/pubmed/29547565 http://dx.doi.org/10.3390/ijms19030886

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