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Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization
Increased plasma homocysteinemia is considered a risk factor of dementia, including Alzheimer’s disease (AD) and vascular dementia. However, the reason elevated plasma homocysteinemia increases the risk of dementia remains unknown. A pathological hallmark of AD is neurofibrillary tangles (NFTs) that...
Autores principales: | Shirafuji, Norimichi, Hamano, Tadanori, Yen, Shu-Hui, Kanaan, Nicholas M., Yoshida, Hirotaka, Hayashi, Kouji, Ikawa, Masamichi, Yamamura, Osamu, Kuriyama, Masaru, Nakamoto, Yasunari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877752/ https://www.ncbi.nlm.nih.gov/pubmed/29562600 http://dx.doi.org/10.3390/ijms19030891 |
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